Jensen O - Search Results

1

Comprehensive characterization of the OCT1 phenylalanine-244-alanine substitution reveals highly substrate-dependent effects on transporter function.

Wittern CI, Schröder S, Jensen O, Brockmöller J, Gebauer L. Wittern CI, et al. Among authors: jensen o. J Biol Chem. 2024 Nov;300(11):107835. doi: 10.1016/j.jbc.2024.107835. Epub 2024 Sep 27. J Biol Chem. 2024. PMID: 39342994 Free PMC article.

2

Substrates and Inhibitors of the Organic Cation Transporter 3 and Comparison with OCT1 and OCT2.

Gebauer L, Jensen O, Brockmöller J, Dücker C. Gebauer L, et al. Among authors: jensen o. J Med Chem. 2022 Sep 22;65(18):12403-12416. doi: 10.1021/acs.jmedchem.2c01075. Epub 2022 Sep 6. J Med Chem. 2022. PMID: 36067397

3

Cellular Uptake of Psychostimulants - Are High- and Low-Affinity Organic Cation Transporters Drug Traffickers?

Jensen O, Rafehi M, Gebauer L, Brockmöller J. Jensen O, et al. Front Pharmacol. 2021 Jan 20;11:609811. doi: 10.3389/fphar.2020.609811. eCollection 2020. Front Pharmacol. 2021. PMID: 33551812 Free PMC article.

4

Identification of Novel High-Affinity Substrates of OCT1 Using Machine Learning-Guided Virtual Screening and Experimental Validation.

Jensen O, Brockmöller J, Dücker C. Jensen O, et al. J Med Chem. 2021 Mar 11;64(5):2762-2776. doi: 10.1021/acs.jmedchem.0c02047. Epub 2021 Feb 19. J Med Chem. 2021. PMID: 33606526

5

Overlap and Specificity in the Substrate Spectra of Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3.

Gebauer L, Jensen O, Neif M, Brockmöller J, Dücker C. Gebauer L, et al. Among authors: jensen o. Int J Mol Sci. 2021 Nov 26;22(23):12816. doi: 10.3390/ijms222312816. Int J Mol Sci. 2021. PMID: 34884618 Free PMC article.

6

Molecular basis for stereoselective transport of fenoterol by the organic cation transporters 1 and 2.

Gebauer L, Arul Murugan N, Jensen O, Brockmöller J, Rafehi M. Gebauer L, et al. Among authors: jensen o. Biochem Pharmacol. 2022 Mar;197:114871. doi: 10.1016/j.bcp.2021.114871. Epub 2021 Dec 10. Biochem Pharmacol. 2022. PMID: 34902340

7

Relationships between Inhibition, Transport and Enhanced Transport via the Organic Cation Transporter 1.

Jensen O, Gebauer L, Brockmöller J, Dücker C. Jensen O, et al. Int J Mol Sci. 2022 Feb 11;23(4):2007. doi: 10.3390/ijms23042007. Int J Mol Sci. 2022. PMID: 35216120 Free PMC article.

8

Substrates of the Human Brain Proton-Organic Cation Antiporter and Comparison with Organic Cation Transporter 1 Activities.

Doetsch DA, Ansari S, Jensen O, Gebauer L, Dücker C, Brockmöller J, Sachkova A. Doetsch DA, et al. Among authors: jensen o. Int J Mol Sci. 2022 Jul 29;23(15):8430. doi: 10.3390/ijms23158430. Int J Mol Sci. 2022. PMID: 35955563 Free PMC article.

9

Atypical Substrates of the Organic Cation Transporter 1.

Redeker KM, Jensen O, Gebauer L, Meyer-Tönnies MJ, Brockmöller J. Redeker KM, et al. Among authors: jensen o. Biomolecules. 2022 Nov 9;12(11):1664. doi: 10.3390/biom12111664. Biomolecules. 2022. PMID: 36359014 Free PMC article.

10

Combined and independent effects of OCT1 and CYP2D6 on the cellular disposition of drugs.

Gebauer L, Dücker C, Jensen O, Brockmöller J. Gebauer L, et al. Among authors: jensen o. Biomed Pharmacother. 2023 May;161:114454. doi: 10.1016/j.biopha.2023.114454. Epub 2023 Mar 3. Biomed Pharmacother. 2023. PMID: 36871537 Free article.

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