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Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice.
Tsitkanou S, Morena da Silva F, Cabrera AR, Schrems ER, Muhyudin R, Koopmans PJ, Khadgi S, Lim S, Delfinis LJ, Washington TA, Murach KA, Perry CGR, Greene NP. Tsitkanou S, et al. Among authors: lim s. Am J Physiol Cell Physiol. 2024 Nov 1;327(5):C1308-C1322. doi: 10.1152/ajpcell.00497.2024. Epub 2024 Sep 30. Am J Physiol Cell Physiol. 2024. PMID: 39344417
Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia.
Cabrera AR, Deaver JW, Lim S, Morena da Silva F, Schrems ER, Saling LW, Tsitkanou S, Rosa-Caldwell ME, Wiggs MP, Washington TA, Greene NP. Cabrera AR, et al. Among authors: lim s. J Appl Physiol (1985). 2023 Sep 1;135(3):655-672. doi: 10.1152/japplphysiol.00196.2023. Epub 2023 Aug 3. J Appl Physiol (1985). 2023. PMID: 37535708 Free PMC article.
Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy.
Rosa-Caldwell ME, Lim S, Haynie WA, Brown JL, Deaver JW, Morena Da Silva F, Jansen LT, Lee DE, Wiggs MP, Washington TA, Greene NP. Rosa-Caldwell ME, et al. Among authors: lim s. J Cachexia Sarcopenia Muscle. 2021 Jun;12(3):717-730. doi: 10.1002/jcsm.12693. Epub 2021 Mar 5. J Cachexia Sarcopenia Muscle. 2021. PMID: 33675163 Free PMC article.
A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle.
Jones RG 3rd, Dimet-Wiley A, Haghani A, da Silva FM, Brightwell CR, Lim S, Khadgi S, Wen Y, Dungan CM, Brooke RT, Greene NP, Peterson CA, McCarthy JJ, Horvath S, Watowich SJ, Fry CS, Murach KA. Jones RG 3rd, et al. Among authors: lim s. J Physiol. 2023 Feb;601(4):763-782. doi: 10.1113/JP283836. Epub 2023 Jan 24. J Physiol. 2023. PMID: 36533424 Free PMC article.
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