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Page 1
Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis.
Bauman AA, Sarathy JP, Kaya F, Massoudi LM, Scherman MS, Hastings C, Liu J, Xie M, Brooks EJ, Ramey ME, Jones IL, Benedict ND, Maclaughlin MR, Miller-Dawson JA, Waidyarachchi SL, Butler MM, Bowlin TL, Zimmerman MD, Lenaerts AJ, Meibohm B, Gonzalez-Juarrero M, Lyons MA, Dartois V, Lee RE, Robertson GT. Bauman AA, et al. Among authors: lenaerts aj. Antimicrob Agents Chemother. 2024 Nov 6;68(11):e0071624. doi: 10.1128/aac.00716-24. Epub 2024 Sep 30. Antimicrob Agents Chemother. 2024. PMID: 39345140 Free PMC article.
Drug distribution and efficacy of the DprE1 inhibitor BTZ-043 in the C3HeB/FeJ mouse tuberculosis model.
Ramey ME, Kaya F, Bauman AA, Massoudi LM, Sarathy JP, Zimmerman MD, Scott DWL, Job AM, Miller-Dawson JA, Podell BK, Lyons MA, Dartois V, Lenaerts AJ, Robertson GT. Ramey ME, et al. Among authors: lenaerts aj. Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0059723. doi: 10.1128/aac.00597-23. Epub 2023 Oct 4. Antimicrob Agents Chemother. 2023. PMID: 37791784 Free PMC article.
A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents.
Hurdle JG, Lee RB, Budha NR, Carson EI, Qi J, Scherman MS, Cho SH, McNeil MR, Lenaerts AJ, Franzblau SG, Meibohm B, Lee RE. Hurdle JG, et al. Among authors: lenaerts aj. J Antimicrob Chemother. 2008 Nov;62(5):1037-45. doi: 10.1093/jac/dkn307. Epub 2008 Aug 7. J Antimicrob Chemother. 2008. PMID: 18693235 Free PMC article.
A physiologically based pharmacokinetic model of rifampin in mice.
Lyons MA, Reisfeld B, Yang RS, Lenaerts AJ. Lyons MA, et al. Among authors: lenaerts aj. Antimicrob Agents Chemother. 2013 Apr;57(4):1763-71. doi: 10.1128/AAC.01567-12. Epub 2013 Jan 28. Antimicrob Agents Chemother. 2013. PMID: 23357766 Free PMC article.
Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas.
Irwin SM, Gruppo V, Brooks E, Gilliland J, Scherman M, Reichlen MJ, Leistikow R, Kramnik I, Nuermberger EL, Voskuil MI, Lenaerts AJ. Irwin SM, et al. Among authors: lenaerts aj. Antimicrob Agents Chemother. 2014 Jul;58(7):4026-34. doi: 10.1128/AAC.02565-14. Epub 2014 May 5. Antimicrob Agents Chemother. 2014. PMID: 24798275 Free PMC article.
In vivo efficacy of apramycin in murine infection models.
Meyer M, Freihofer P, Scherman M, Teague J, Lenaerts A, Böttger EC. Meyer M, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6938-41. doi: 10.1128/AAC.03239-14. Epub 2014 Aug 18. Antimicrob Agents Chemother. 2014. PMID: 25136009 Free PMC article.
95 results