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435 results

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Page 1
Amplification of Protein Expression by Self-Amplifying mRNA Delivered in Lipid Nanoparticles Containing a β-Aminoester Ionizable Lipid Correlates with Reduced Innate Immune Activation.
De Lombaerde E, Cui X, Chen Y, Zhong Z, Deckers J, Mencarelli G, Opsomer L, Wang H, De Baere J, Lienenklaus S, Lambrecht BN, Sanders NN, De Geest BG. De Lombaerde E, et al. Among authors: lambrecht bn. ACS Nano. 2024 Oct 15;18(41):28311-28324. doi: 10.1021/acsnano.4c09677. Epub 2024 Oct 1. ACS Nano. 2024. PMID: 39352021
Lipid Nanoparticle Delivery Alters the Adjuvanticity of the TLR9 Agonist CpG by Innate Immune Activation in Lymphoid Tissue.
Zhong Z, Chen Y, Deswarte K, Lauwers H, De Lombaerde E, Cui X, Van Herck S, Ye T, Gontsarik M, Lienenklaus S, Sanders NN, Lambrecht BN, De Koker S, De Geest BG. Zhong Z, et al. Among authors: lambrecht bn. Adv Healthc Mater. 2023 Dec;12(32):e2301687. doi: 10.1002/adhm.202301687. Epub 2023 Oct 11. Adv Healthc Mater. 2023. PMID: 37772637
Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity.
Lamoot A, Jangra S, Laghlali G, Warang P, Singh G, Chang LA, Park SC, Singh G, De Swarte K, Zhong Z, Louage B, De Lombaerde E, Ye T, Chen Y, Cuadrado-Castano S, Lienenklaus S, Sanders NN, Lambrecht BN, García-Sastre A, Schotsaert M, De Geest BG. Lamoot A, et al. Among authors: lambrecht bn. Small. 2024 Mar;20(10):e2306892. doi: 10.1002/smll.202306892. Epub 2023 Oct 22. Small. 2024. PMID: 37867244 Free PMC article.
CO-DELIVERY of glutamic acid-extended peptide antigen and imidazoquinoline TLR7/8 agonist via ionizable lipid nanoparticles induces protective anti-tumor immunity.
Ye T, Zhong Z, Cappellesso F, Deswarte K, Chen Y, Lauwers H, De Lombaerde E, Gontsarik M, Lienenklaus S, Van Lysebetten D, Sanders NN, Lambrecht BN, De Koker S, Laoui D, De Geest BG. Ye T, et al. Among authors: lambrecht bn. Biomaterials. 2024 Dec;311:122693. doi: 10.1016/j.biomaterials.2024.122693. Epub 2024 Jun 27. Biomaterials. 2024. PMID: 38996672
PH-Triggered, Lymph Node Focused Immunodrug Release by Polymeric 2-Propionic-3-Methyl-maleic Anhydrides with Cholesteryl End Groups.
Heck AG, Medina-Montano C, Zhong Z, Deswarte K, Eigen K, Stickdorn J, Kockelmann J, Scherger M, Sanders NN, Lienenklaus S, Lambrecht BN, Grabbe S, De Geest BG, Nuhn L. Heck AG, et al. Among authors: lambrecht bn. Adv Healthc Mater. 2024 Dec;13(32):e2402875. doi: 10.1002/adhm.202402875. Epub 2024 Sep 23. Adv Healthc Mater. 2024. PMID: 39313985 Free PMC article.
Single-cell proteomics and transcriptomics capture eosinophil development and identify the role of IL-5 in their lineage transit amplification.
Jorssen J, Van Hulst G, Mollers K, Pujol J, Petrellis G, Baptista AP, Schetters S, Baron F, Caers J, Lambrecht BN, Dewals BG, Bureau F, Desmet CJ. Jorssen J, et al. Among authors: lambrecht bn. Immunity. 2024 Jul 9;57(7):1549-1566.e8. doi: 10.1016/j.immuni.2024.04.027. Epub 2024 May 21. Immunity. 2024. PMID: 38776917
TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice.
Ruiz Pérez M, Maueröder C, Steels W, Verstraeten B, Lameire S, Xie W, Wyckaert L, Huysentruyt J, Divert T, Roelandt R, Gonçalves A, De Rycke R, Ravichandran K, Lambrecht BN, Taghon T, Leclercq G, Vandenabeele P, Tougaard P. Ruiz Pérez M, et al. Among authors: lambrecht bn. Cell Mol Immunol. 2024 Aug;21(8):807-825. doi: 10.1038/s41423-024-01180-8. Epub 2024 Jun 5. Cell Mol Immunol. 2024. PMID: 38839915 Free PMC article.
RIPK1 protects naive and regulatory T cells from TNFR1-induced apoptosis.
Huysentruyt J, Steels W, Ruiz Perez M, Verstraeten B, Vadi M, Divert T, Flies K, Takahashi N, Lambrecht BN, Declercq W, Vanden Berghe T, Maelfait J, Vandenabeele P, Tougaard P. Huysentruyt J, et al. Among authors: lambrecht bn. Cell Death Differ. 2024 Jun;31(6):820-832. doi: 10.1038/s41418-024-01301-w. Epub 2024 May 11. Cell Death Differ. 2024. PMID: 38734851 Free PMC article.
Shared lung and joint T cell repertoire in early rheumatoid arthritis driven by cigarette smoking.
Venken K, Jarlborg M, Stevenaert F, Malfait TLA, Vlieghe C, Abraham Y, Manuello T, Decruy T, Vanhee S, Wils H, Peeters PJ, Carron P, Van den Bosch F, Van Tendeloo V, Lambrecht BN, Wittoek R, Jacques P, Elewaut D. Venken K, et al. Among authors: lambrecht bn. Ann Rheum Dis. 2024 Nov 8:ard-2024-226284. doi: 10.1136/ard-2024-226284. Online ahead of print. Ann Rheum Dis. 2024. PMID: 39521450
435 results