Klinger B - Search Results

1

Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network.

Klinger B, Rausch I, Sieber A, Kutz H, Kruse V, Kirchner M, Mertins P, Kieser A, Blüthgen N, Kube D. Klinger B, et al. PLoS Comput Biol. 2024 Oct 1;20(10):e1012488. doi: 10.1371/journal.pcbi.1012488. eCollection 2024 Oct. PLoS Comput Biol. 2024. PMID: 39352924 Free PMC article.

2

Network quantification of EGFR signaling unveils potential for targeted combination therapy.

Klinger B, Sieber A, Fritsche-Guenther R, Witzel F, Berry L, Schumacher D, Yan Y, Durek P, Merchant M, Schäfer R, Sers C, Blüthgen N. Klinger B, et al. Mol Syst Biol. 2013;9:673. doi: 10.1038/msb.2013.29. Mol Syst Biol. 2013. PMID: 23752269 Free PMC article.

3

Modeling unveils sex differences of signaling networks in mouse embryonic stem cells.

Sultana Z, Dorel M, Klinger B, Sieber A, Dunkel I, Blüthgen N, Schulz EG. Sultana Z, et al. Among authors: klinger b. Mol Syst Biol. 2023 Nov 9;19(11):e11510. doi: 10.15252/msb.202211510. Epub 2023 Sep 21. Mol Syst Biol. 2023. PMID: 37735975 Free PMC article.

4

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.

Dorel M, Klinger B, Mari T, Toedling J, Blanc E, Messerschmidt C, Nadler-Holly M, Ziehm M, Sieber A, Hertwig F, Beule D, Eggert A, Schulte JH, Selbach M, Blüthgen N. Dorel M, et al. Among authors: klinger b. PLoS Comput Biol. 2021 Nov 4;17(11):e1009515. doi: 10.1371/journal.pcbi.1009515. eCollection 2021 Nov. PLoS Comput Biol. 2021. PMID: 34735429 Free PMC article.

5

An immediate-late gene expression module decodes ERK signal duration.

Uhlitz F, Sieber A, Wyler E, Fritsche-Guenther R, Meisig J, Landthaler M, Klinger B, Blüthgen N. Uhlitz F, et al. Among authors: klinger b. Mol Syst Biol. 2017 May 3;13(5):928. doi: 10.15252/msb.20177554. Mol Syst Biol. 2017. PMID: 28468958 Free PMC article.

6

Reverse engineering gene regulatory networks by modular response analysis - a benchmark.

Klinger B, Blüthgen N. Klinger B, et al. Essays Biochem. 2018 Oct 26;62(4):535-547. doi: 10.1042/EBC20180012. Print 2018 Oct 26. Essays Biochem. 2018. PMID: 30315094 Review.

7

Drug Resistance Mechanisms in Colorectal Cancer Dissected with Cell Type-Specific Dynamic Logic Models.

Eduati F, Doldàn-Martelli V, Klinger B, Cokelaer T, Sieber A, Kogera F, Dorel M, Garnett MJ, Blüthgen N, Saez-Rodriguez J. Eduati F, et al. Among authors: klinger b. Cancer Res. 2017 Jun 15;77(12):3364-3375. doi: 10.1158/0008-5472.CAN-17-0078. Epub 2017 Apr 5. Cancer Res. 2017. PMID: 28381545 Free PMC article.

8

Perturbation-response genes reveal signaling footprints in cancer gene expression.

Schubert M, Klinger B, Klünemann M, Sieber A, Uhlitz F, Sauer S, Garnett MJ, Blüthgen N, Saez-Rodriguez J. Schubert M, et al. Among authors: klinger b. Nat Commun. 2018 Jan 2;9(1):20. doi: 10.1038/s41467-017-02391-6. Nat Commun. 2018. PMID: 29295995 Free PMC article.

9

Modelling signalling networks from perturbation data.

Dorel M, Klinger B, Gross T, Sieber A, Prahallad A, Bosdriesz E, Wessels LFA, Blüthgen N. Dorel M, et al. Among authors: klinger b. Bioinformatics. 2018 Dec 1;34(23):4079-4086. doi: 10.1093/bioinformatics/bty473. Bioinformatics. 2018. PMID: 29931053

10

Comparative Network Reconstruction using mixed integer programming.

Bosdriesz E, Prahallad A, Klinger B, Sieber A, Bosma A, Bernards R, Blüthgen N, Wessels LFA. Bosdriesz E, et al. Among authors: klinger b. Bioinformatics. 2018 Sep 1;34(17):i997-i1004. doi: 10.1093/bioinformatics/bty616. Bioinformatics. 2018. PMID: 30423075 Free PMC article.

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