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Page 1
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Carling GK, Fan L, Foxe NR, Norman K, Wong MY, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A, Ye P, Chen H, Huang Y, Amin S, Sereda R, Lopez-Lee C, Zacharioudakis E, Chen X, Xu J, Cheng F, Gavathiotis E, Cuervo AM, Holtzman DM, Mok SA, Sinha SC, Sidoli S, Ratan RR, Luo W, Gong S, Gan L. Carling GK, et al. Among authors: sinha sc. Neuron. 2024 Dec 4;112(23):3877-3896.e8. doi: 10.1016/j.neuron.2024.09.006. Epub 2024 Sep 30. Neuron. 2024. PMID: 39353433 Free article.
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Udeochu JC, Amin S, Huang Y, Fan L, Torres ERS, Carling GK, Liu B, McGurran H, Coronas-Samano G, Kauwe G, Mousa GA, Wong MY, Ye P, Nagiri RK, Lo I, Holtzman J, Corona C, Yarahmady A, Gill MT, Raju RM, Mok SA, Gong S, Luo W, Zhao M, Tracy TE, Ratan RR, Tsai LH, Sinha SC, Gan L. Udeochu JC, et al. Among authors: sinha sc. Nat Neurosci. 2023 May;26(5):737-750. doi: 10.1038/s41593-023-01315-6. Epub 2023 Apr 24. Nat Neurosci. 2023. PMID: 37095396 Free PMC article.
Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.
Parra Bravo C, Krukowski K, Barker S, Wang C, Li Y, Fan L, Vázquez-Rosa E, Shin MK, Wong MY, McCullough LD, Kitagawa RS, Choi HA, Cacace A, Sinha SC, Pieper AA, Rosi S, Chen X, Gan L. Parra Bravo C, et al. Among authors: sinha sc. Mol Neurodegener. 2024 Jun 24;19(1):51. doi: 10.1186/s13024-024-00733-9. Mol Neurodegener. 2024. PMID: 38915105 Free PMC article.
Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.
Lopez-Lee C, Kodama L, Fan L, Zhu D, Zhu J, Wong MY, Ye P, Norman K, Foxe NR, Ijaz L, Yu F, Chen H, Carling GK, Torres ER, Kim RD, Dubal DB, Liddelow SA, Sinha SC, Luo W, Gan L. Lopez-Lee C, et al. Among authors: sinha sc. Science. 2024 Nov 29;386(6725):eadk7844. doi: 10.1126/science.adk7844. Epub 2024 Nov 29. Science. 2024. PMID: 39607927
A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer's disease vulnerable neurons.
Rodriguez-Rodriguez P, Arroyo-Garcia LE, Tsagkogianni C, Li L, Wang W, Végvári Á, Salas-Allende I, Plautz Z, Cedazo-Minguez A, Sinha SC, Troyanskaya O, Flajolet M, Yao V, Roussarie JP. Rodriguez-Rodriguez P, et al. Among authors: sinha sc. Brain. 2024 Jul 5;147(7):2384-2399. doi: 10.1093/brain/awae051. Brain. 2024. PMID: 38462574 Free PMC article.
Editorial: Spotlight on North America - chemical sciences.
Sinha SC, Ummadisetti CR, Laali KK, Bao K, Bhupathiraju NVSDK, Ojima I. Sinha SC, et al. Front Chem. 2024 Dec 3;12:1531189. doi: 10.3389/fchem.2024.1531189. eCollection 2024. Front Chem. 2024. PMID: 39691827 Free PMC article. No abstract available.
114 results