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Bioreactor-produced iPSCs-derived dopaminergic neuron-containing neural microtissues innervate and normalize rotational bias in a dose-dependent manner in a Parkinson rat model.
Prudon N, Cordero-Espinoza L, Abarkan M, Gurchenkov B, Morel C, Lepleux M, De Luca V, Lartigue M, Cabanas H, Pujol N, Milvoy L, Morand P, Moncaubeig F, Wurtz H, Poinçot L, De Marco M, Jonckeau A, Pletenka J, Luquet E, Sovera A, Hardoüin J, Neves IJ, Machado-Hitau A, Schmit K, Piouceau L, Guilbert S, Manache-Alberici L, Lanero Fidalgo M, Dabée G, Dufourd T, Schroeder J, Alessandri K, Bezard E, Faggiani E, Feyeux M. Prudon N, et al. Among authors: sovera a. Neurotherapeutics. 2024 Sep;21(5):e00436. doi: 10.1016/j.neurot.2024.e00436. Epub 2024 Oct 1. Neurotherapeutics. 2024. PMID: 39353832 Free PMC article.
Lack of gastric adverse effects of erdosteine in rats and men.
De Giovanni L, Fregnan GB, Rabitti C, Murari G, Amato A, Sovera A, Civello IM. De Giovanni L, et al. Among authors: sovera a. Int J Clin Pharmacol Ther Toxicol. 1991 Jul;29(7):269-73. Int J Clin Pharmacol Ther Toxicol. 1991. PMID: 1889913 Clinical Trial.