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LRRK2 regulates production of reactive oxygen species in cell and animal models of Parkinson's disease.
Keeney MT, Rocha EM, Hoffman EK, Farmer K, Di Maio R, Weir J, Wagner WG, Hu X, Clark CL, Castro SL, Scheirer A, Fazzari M, De Miranda BR, Pintchovski SA, Shrader WD, Pagano PJ, Hastings TG, Greenamyre JT. Keeney MT, et al. Among authors: fazzari m. Sci Transl Med. 2024 Oct 2;16(767):eadl3438. doi: 10.1126/scitranslmed.adl3438. Epub 2024 Oct 2. Sci Transl Med. 2024. PMID: 39356746
NADPH oxidase 2 activity in Parkinson's disease.
Keeney MT, Hoffman EK, Farmer K, Bodle CR, Fazzari M, Zharikov A, Castro SL, Hu X, Mortimer A, Kofler JK, Cifuentes-Pagano E, Pagano PJ, Burton EA, Hastings TG, Greenamyre JT, Di Maio R. Keeney MT, et al. Among authors: fazzari m. Neurobiol Dis. 2022 Aug;170:105754. doi: 10.1016/j.nbd.2022.105754. Epub 2022 May 13. Neurobiol Dis. 2022. PMID: 35577065 Free PMC article.
Neuroprotective actions of a fatty acid nitroalkene in Parkinson's disease.
Di Maio R, Keeney MT, Cechova V, Mortimer A, Sekandari A, Rowart P, Greenamyre JT, Freeman BA, Fazzari M. Di Maio R, et al. Among authors: fazzari m. NPJ Parkinsons Dis. 2023 Apr 7;9(1):55. doi: 10.1038/s41531-023-00502-3. NPJ Parkinsons Dis. 2023. PMID: 37029127 Free PMC article.
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation.
Yuan S, Hahn SA, Miller MP, Sanker S, Calderon MJ, Sullivan M, Dosunmu-Ogunbi AM, Fazzari M, Li Y, Reynolds M, Wood KC, St Croix CM, Stolz D, Cifuentes-Pagano E, Navas P, Shiva S, Schopfer FJ, Pagano PJ, Straub AC. Yuan S, et al. Among authors: fazzari m. Redox Biol. 2021 Nov;47:102166. doi: 10.1016/j.redox.2021.102166. Epub 2021 Oct 14. Redox Biol. 2021. PMID: 34656824 Free PMC article.
Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis.
Khoo NKH, Fazzari M, Chartoumpekis DV, Li L, Guimaraes DA, Arteel GE, Shiva S, Freeman BA. Khoo NKH, et al. Among authors: fazzari m. Redox Biol. 2019 Apr;22:101132. doi: 10.1016/j.redox.2019.101132. Epub 2019 Feb 1. Redox Biol. 2019. PMID: 30769284 Free PMC article.
219 results