Ding J - Search Results

1

Discovery of Orally Active Phenylquinoline-Based Soluble Epoxide Hydrolase Inhibitors with Anti-Inflammatory and Analgesic Activity.

Ding J, Zhu MZ, Liu SM, Liu RC, Xu S, Shehzadi K, Ma HL, Yu MJ, Zhu XH, Liang JH. Ding J, et al. J Med Chem. 2024 Oct 24;67(20):18412-18447. doi: 10.1021/acs.jmedchem.4c01766. Epub 2024 Oct 3. J Med Chem. 2024. PMID: 39361006

2

Discovery of [1,2,4]-triazolo [1,5-a]pyrimidine-7(4H)-one derivatives as positive modulators of GABA_A1 receptor with potent anticonvulsant activity and low toxicity.

Huang L, Ding J, Li M, Hou Z, Geng Y, Li X, Yu H. Huang L, et al. Among authors: ding j. Eur J Med Chem. 2020 Jan 1;185:111824. doi: 10.1016/j.ejmech.2019.111824. Epub 2019 Oct 31. Eur J Med Chem. 2020. PMID: 31708184

3

Design and synthesis of novel macrolones bridged with linkers from 11,12-positions of macrolides.

Liu XP, Lv W, Zhao F, Ding J, Zhang JR, Xue F, Zhang JZ, Liu LY, Cushman M, Li Y, Liang JH. Liu XP, et al. Among authors: ding j. Bioorg Med Chem Lett. 2022 Jul 15;68:128761. doi: 10.1016/j.bmcl.2022.128761. Epub 2022 Apr 26. Bioorg Med Chem Lett. 2022. PMID: 35483593

4

Synthesis of Trifluoromethylated Monoterpenes by an Engineered Cytochrome P450.

Yuan F, Ding J, Sun Y, Liang J, Luo Y, Yu Y. Yuan F, et al. Among authors: ding j. Chemistry. 2024 Feb 16;30(10):e202302936. doi: 10.1002/chem.202302936. Epub 2024 Jan 3. Chemistry. 2024. PMID: 38012074

5

Discovery of a novel lead characterized by a stilbene-extended scaffold against sepsis as soluble epoxide hydrolase inhibitors.

Feng ZQ, Ding J, Zhu MZ, Xie WS, Liu RC, Liu SS, Liu SM, Yu MJ, Zhu XH, Liang JH. Feng ZQ, et al. Among authors: ding j. Eur J Med Chem. 2024 Feb 15;266:116113. doi: 10.1016/j.ejmech.2023.116113. Epub 2024 Jan 3. Eur J Med Chem. 2024. PMID: 38215588

6

Design, synthesis and structure-activity relationships of novel non-ketolides: 9-Oxime clarithromycin featured with seven-to thirteen-atom-length diamine linkers at 3-OH.

Ma CX, Liu WT, Li XM, Ding J, Liu SM, Xue F, Li Y, Liang JH. Ma CX, et al. Among authors: ding j. Eur J Med Chem. 2024 Oct 5;276:116630. doi: 10.1016/j.ejmech.2024.116630. Epub 2024 Jun 25. Eur J Med Chem. 2024. PMID: 38972081

7

Discovery of glycosidated glycyrrhetinic acid derivatives: Natural product-based soluble epoxide hydrolase inhibitors.

Liu Q, Wang YX, Ge ZH, Zhu MZ, Ding J, Wang H, Liu SM, Liu RC, Li C, Yu MJ, Feng Y, Zhu XH, Liang JH. Liu Q, et al. Among authors: ding j. Eur J Med Chem. 2024 Dec 15;280:116937. doi: 10.1016/j.ejmech.2024.116937. Epub 2024 Oct 9. Eur J Med Chem. 2024. PMID: 39413443

8

Redesigning Berberines and Sanguinarines to Target Soluble Epoxide Hydrolase for Enhanced Anti-Inflammatory Efficacy.

Liu XZ, Du XY, Xie WS, Ding J, Zhu MZ, Feng ZQ, Wang H, Feng Y, Yu MJ, Liu SM, Liu WT, Zhu XH, Liang JH. Liu XZ, et al. Among authors: ding j. J Med Chem. 2024 Dec 10. doi: 10.1021/acs.jmedchem.4c02202. Online ahead of print. J Med Chem. 2024. PMID: 39658523

9

Synthesis and in vitro anti-epileptic activities of novel [1,2,4]-triazolo[1,5-a]pyrimidin-7(4H)-one derivatives.

Ding J, Cao FD, Geng YR, Tian Y, Li P, Li XF, Huang LJ. Ding J, et al. J Asian Nat Prod Res. 2019 Dec;21(12):1190-1204. doi: 10.1080/10286020.2018.1529030. Epub 2018 Dec 28. J Asian Nat Prod Res. 2019. PMID: 30593254

10

Semi-synthesis and antitumor activity of 6-isomers of 5, 8-O-dimethyl acylshikonin derivatives.

Zhou W, Zhang X, Xiao L, Ding J, Liu QH, Li SS. Zhou W, et al. Among authors: ding j. Eur J Med Chem. 2011 Aug;46(8):3420-7. doi: 10.1016/j.ejmech.2011.05.006. Epub 2011 May 12. Eur J Med Chem. 2011. PMID: 21620530

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