Yu MJ - Search Results

1

Discovery of Orally Active Phenylquinoline-Based Soluble Epoxide Hydrolase Inhibitors with Anti-Inflammatory and Analgesic Activity.

Ding J, Zhu MZ, Liu SM, Liu RC, Xu S, Shehzadi K, Ma HL, Yu MJ, Zhu XH, Liang JH. Ding J, et al. Among authors: yu mj. J Med Chem. 2024 Oct 24;67(20):18412-18447. doi: 10.1021/acs.jmedchem.4c01766. Epub 2024 Oct 3. J Med Chem. 2024. PMID: 39361006

2

Design, Synthesis and Biological Evaluation of Conjugates of 3-O-Descladinose-azithromycin and Nucleobases against rRNA A2058G- or A2059G-Mutated Strains.

Lian X, Liu W, Fan B, Yu M, Liang J. Lian X, et al. Molecules. 2023 Jan 30;28(3):1327. doi: 10.3390/molecules28031327. Molecules. 2023. PMID: 36770992 Free PMC article.

3

Structure-Based Drug Design of RdRp Inhibitors against SARS-CoV-2.

Shehzadi K, Saba A, Yu M, Liang J. Shehzadi K, et al. Top Curr Chem (Cham). 2023 Jun 15;381(5):22. doi: 10.1007/s41061-023-00432-x. Top Curr Chem (Cham). 2023. PMID: 37318607 Review.

4

De Novo Potent Peptide Nucleic Acid Antisense Oligomer Inhibitors Targeting SARS-CoV-2 RNA-Dependent RNA Polymerase via Structure-Guided Drug Design.

Shehzadi K, Yu M, Liang J. Shehzadi K, et al. Int J Mol Sci. 2023 Dec 14;24(24):17473. doi: 10.3390/ijms242417473. Int J Mol Sci. 2023. PMID: 38139312 Free PMC article.

5

Discovery of a novel lead characterized by a stilbene-extended scaffold against sepsis as soluble epoxide hydrolase inhibitors.

Feng ZQ, Ding J, Zhu MZ, Xie WS, Liu RC, Liu SS, Liu SM, Yu MJ, Zhu XH, Liang JH. Feng ZQ, et al. Among authors: yu mj. Eur J Med Chem. 2024 Feb 15;266:116113. doi: 10.1016/j.ejmech.2023.116113. Epub 2024 Jan 3. Eur J Med Chem. 2024. PMID: 38215588

6

Rationally Designed Novel Antimicrobial Peptides Targeting Chitin Synthase for Combating Soybean Phytophthora Blight.

Ran Y, Shehzadi K, Liang JH, Yu MJ. Ran Y, et al. Among authors: yu mj. Int J Mol Sci. 2024 Mar 20;25(6):3512. doi: 10.3390/ijms25063512. Int J Mol Sci. 2024. PMID: 38542484 Free PMC article.

7

Unraveling the Mechanisms of Cannabidiol's Pharmacological Actions: A Comprehensive Research Overview.

Kalsoom I, Shehzadi K, Li HS, Wen HL, Yu MJ. Kalsoom I, et al. Among authors: yu mj. Top Curr Chem (Cham). 2024 Jun 3;382(2):20. doi: 10.1007/s41061-024-00465-w. Top Curr Chem (Cham). 2024. PMID: 38829467 Review.

8

Unlocking the Reverse Targeting Mechanisms of Cannabidiol: Unveiling New Therapeutic Avenues.

Zeng W, Wang Y, Gao R, Wen H, Yu M. Zeng W, et al. J Med Chem. 2024 Aug 22;67(16):14574-14585. doi: 10.1021/acs.jmedchem.4c01353. Epub 2024 Aug 2. J Med Chem. 2024. PMID: 39092992

9

Discovery of glycosidated glycyrrhetinic acid derivatives: Natural product-based soluble epoxide hydrolase inhibitors.

Liu Q, Wang YX, Ge ZH, Zhu MZ, Ding J, Wang H, Liu SM, Liu RC, Li C, Yu MJ, Feng Y, Zhu XH, Liang JH. Liu Q, et al. Among authors: yu mj. Eur J Med Chem. 2024 Dec 15;280:116937. doi: 10.1016/j.ejmech.2024.116937. Epub 2024 Oct 9. Eur J Med Chem. 2024. PMID: 39413443

10

Redesigning Berberines and Sanguinarines to Target Soluble Epoxide Hydrolase for Enhanced Anti-Inflammatory Efficacy.

Liu XZ, Du XY, Xie WS, Ding J, Zhu MZ, Feng ZQ, Wang H, Feng Y, Yu MJ, Liu SM, Liu WT, Zhu XH, Liang JH. Liu XZ, et al. Among authors: yu mj. J Med Chem. 2024 Dec 26;67(24):22168-22190. doi: 10.1021/acs.jmedchem.4c02202. Epub 2024 Dec 10. J Med Chem. 2024. PMID: 39658523

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