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Epithelial neutrophil localization and tight junction Claudin-2 expression are innovative outcome predictors in inflammatory bowel disease.
Zammarchi I, Santacroce G, Puga-Tejada M, Hayes B, Crotty R, O'Driscoll E, Majumder S, Kaczmarczyk W, Maeda Y, McCarthy J, Sugrue K, O'Sullivan C, Burke L, Ghosh S, Iacucci M. Zammarchi I, et al. Among authors: mccarthy j. United European Gastroenterol J. 2024 Nov;12(9):1155-1166. doi: 10.1002/ueg2.12677. Epub 2024 Oct 3. United European Gastroenterol J. 2024. PMID: 39361538 Free PMC article.
Effectiveness, safety, and cost of combination advanced therapies in inflammatory bowel disease.
McShane C, Varley R, Fennessy A, Byron C, Campion JR, Hazel K, Costigan C, Ring E, Marrinan A, Judge C, Sugrue K, Cullen G, Dunne C, Hartery K, Iacucci M, Kelly O, Leyden J, McKiernan S, O'Toole A, Sheridan J, Slattery E, Boland K, McNamara D, Egan L, Ghosh S, Doherty G, McCarthy J, Kevans D. McShane C, et al. Among authors: mccarthy j. Dig Liver Dis. 2024 Sep 21:S1590-8658(24)00973-3. doi: 10.1016/j.dld.2024.08.055. Online ahead of print. Dig Liver Dis. 2024. PMID: 39307602
Combining Therapies in Inflammatory Bowel Disease: End of the Line or a New Era?
Judge C, Saeidi R, Sugrue K, Rabbitt L, Keogh A, Byron C, Zulquernain SA, Gleeson S, O'Toole A, Buckley M, Slattery E, Doherty G, McCarthy J. Judge C, et al. Among authors: mccarthy j. Inflamm Bowel Dis. 2021 May 17;27(6):956-959. doi: 10.1093/ibd/izab028. Inflamm Bowel Dis. 2021. PMID: 33544119 No abstract available.
I-CARE, a European Prospective Cohort Study Assessing Safety and Effectiveness of Biologics in Inflammatory Bowel Disease.
Peyrin-Biroulet L, Rahier JF, Kirchgesner J, Abitbol V, Shaji S, Armuzzi A, Karmiris K, Gisbert JP, Bossuyt P, Helwig U, Burisch J, Yanai H, Doherty GA, Magro F, Molnar T, Löwenberg M, Halfvarson J, Zagorowicz E, Rousseau H, Baumann C, Baert F, Beaugerie L; I-CARE Collaborator Group. Peyrin-Biroulet L, et al. Clin Gastroenterol Hepatol. 2023 Mar;21(3):771-788.e10. doi: 10.1016/j.cgh.2022.09.018. Epub 2022 Sep 22. Clin Gastroenterol Hepatol. 2023. PMID: 36152897 Free article.
Irish data on the safety and efficacy of vedolizumab in the treatment of inflammatory bowel disease.
Judge C, McGettigan N, Ryan T, Hazel K, Singh P, Parihar V, Stack R, O'Connor A, Dunne C, Cullen G, Egan L, Harewood G, MacCarthy F, McKiernan S, Mulcahy H, Murray F, Patchett S, Sheridan J, Cheriyan D, Farrell R, Keohane J, Kelly O, McNamara D, Ryan B, O'Morain C, Sengupta S, O'Toole A, Buckley M, McCarthy J, Doherty G, Kevans D, Slattery E. Judge C, et al. Among authors: mccarthy j. Scand J Gastroenterol. 2020 Jul;55(7):786-794. doi: 10.1080/00365521.2020.1779340. Epub 2020 Jun 16. Scand J Gastroenterol. 2020. PMID: 32544012
Protocol for a multicentred randomised controlled trial investigating the use of personalised golimumab dosing tailored to inflammatory load in ulcerative colitis: the GOAL-ARC study (GLM dose Optimisation to Adequate Levels to Achieve Response in Colitis) led by the INITIAtive group (NCT 0268772).
Sheridan J, Coe CA, Doran P, Egan L, Cullen G, Kevans D, Leyden J, Galligan M, O'Toole A, McCarthy J, Doherty G. Sheridan J, et al. Among authors: mccarthy j. BMJ Open Gastroenterol. 2018 Jan 11;5(1):e000174. doi: 10.1136/bmjgast-2017-000174. eCollection 2018. BMJ Open Gastroenterol. 2018. PMID: 29379609 Free PMC article.
TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells.
Woznicki JA, Saini N, Flood P, Rajaram S, Lee CM, Stamou P, Skowyra A, Bustamante-Garrido M, Regazzoni K, Crawford N, McDade SS, Longley DB, Aza-Blanc P, Shanahan F, Zulquernain SA, McCarthy J, Melgar S, McRae BL, Nally K. Woznicki JA, et al. Among authors: mccarthy j. Cell Death Dis. 2021 Sep 23;12(10):864. doi: 10.1038/s41419-021-04151-3. Cell Death Dis. 2021. PMID: 34556638 Free PMC article.
Human BCL-G regulates secretion of inflammatory chemokines but is dispensable for induction of apoptosis by IFN-γ and TNF-α in intestinal epithelial cells.
Woznicki JA, Flood P, Bustamante-Garrido M, Stamou P, Moloney G, Fanning A, Zulquernain SA, McCarthy J, Shanahan F, Melgar S, Nally K. Woznicki JA, et al. Among authors: mccarthy j. Cell Death Dis. 2020 Jan 27;11(1):68. doi: 10.1038/s41419-020-2263-0. Cell Death Dis. 2020. PMID: 31988296 Free PMC article.
3,455 results