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Reversible covalent c-Jun N-terminal kinase inhibitors targeting a specific cysteine by precision-guided Michael-acceptor warheads.
Bálint D, Póti ÁL, Alexa A, Sok P, Albert K, Torda L, Földesi-Nagy D, Csókás D, Turczel G, Imre T, Szarka E, Fekete F, Bento I, Bojtár M, Palkó R, Szabó P, Monostory K, Pápai I, Soós T, Reményi A. Bálint D, et al. Among authors: palko r. Nat Commun. 2024 Oct 4;15(1):8606. doi: 10.1038/s41467-024-52573-2. Nat Commun. 2024. PMID: 39366946 Free PMC article.
Lens Epithelial Explants Treated with Vitreous Humor Undergo Alterations in Chromatin Landscape with Concurrent Activation of Genes Associated with Fiber Cell Differentiation and Innate Immune Response.
Upreti A, Padula SL, Tangeman JA, Wagner BD, O'Connell MJ, Jaquish TJ, Palko RK, Mantz CJ, Anand D, Lovicu FJ, Lachke SA, Robinson ML. Upreti A, et al. Among authors: palko rk. Cells. 2023 Feb 3;12(3):501. doi: 10.3390/cells12030501. Cells. 2023. PMID: 36766843 Free PMC article.