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High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan.
Gao AW, Alam GE, Zhu Y, Li W, Katsyuba E, Sulc J, Li TY, Li X, Overmyer KA, Lalou A, Mouchiroud L, Sleiman MB, Cornaglia M, Morel JD, Houtkooper RH, Coon JJ, Auwerx J. Gao AW, et al. bioRxiv [Preprint]. 2024 Jan 16:2024.01.15.575638. doi: 10.1101/2024.01.15.575638. bioRxiv. 2024. Update in: Cell Rep. 2024 Oct 22;43(10):114836. doi: 10.1016/j.celrep.2024.114836 PMID: 38293129 Free PMC article. Updated. Preprint.
Reduced ech-6 expression attenuates fat-induced lifespan shortening in C. elegans.
Liu YJ, Gao AW, Smith RL, Janssens GE, Panneman DM, Jongejan A, van Weeghel M, Vaz FM, Silvestrini MJ, Lapierre LR, MacInnes AW, Houtkooper RH. Liu YJ, et al. Among authors: gao aw. Sci Rep. 2022 Mar 1;12(1):3350. doi: 10.1038/s41598-022-07397-9. Sci Rep. 2022. PMID: 35233004 Free PMC article.
Anti-retroviral treatment with zidovudine alters pyrimidine metabolism, reduces translation, and extends healthy longevity via ATF-4.
McIntyre RL, Molenaars M, Schomakers BV, Gao AW, Kamble R, Jongejan A, van Weeghel M, van Kuilenburg ABP, Possemato R, Houtkooper RH, Janssens GE. McIntyre RL, et al. Among authors: gao aw. Cell Rep. 2023 Jan 31;42(1):111928. doi: 10.1016/j.celrep.2022.111928. Epub 2022 Dec 30. Cell Rep. 2023. PMID: 36640360 Free article.
26 results