Liu X - Search Results

1

Activity and phosphatidylcholine transfer protein interactions of skeletal muscle thioesterase Them2 enable hepatic steatosis and insulin resistance.

Xie Y, Liu X, Liu W, Carr LR, Lee LP, Imai N, Ortlund EA, Cohen DE. Xie Y, et al. Among authors: liu x, liu w. J Biol Chem. 2024 Oct 4:107855. doi: 10.1016/j.jbc.2024.107855. Online ahead of print. J Biol Chem. 2024. PMID: 39369989 Free article.

2

High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease.

Krumm CS, Landzberg RS, Ramos-Espiritu L, Adura C, Liu X, Acuna M, Xie Y, Xu X, Tillman MC, Li Y, Glickman JF, Ortlund EA, Ginn JD, Cohen DE. Krumm CS, et al. Among authors: liu x. Mol Metab. 2023 Dec;78:101832. doi: 10.1016/j.molmet.2023.101832. Epub 2023 Oct 30. Mol Metab. 2023. PMID: 38403978 Free PMC article.

3

The nuclear receptor superfamily: A structural perspective.

Weikum ER, Liu X, Ortlund EA. Weikum ER, et al. Among authors: liu x. Protein Sci. 2018 Nov;27(11):1876-1892. doi: 10.1002/pro.3496. Protein Sci. 2018. PMID: 30109749 Free PMC article. Review.

4

First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain-Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthetic Glucocorticoids.

Liu X, Wang Y, Ortlund EA. Liu X, et al. Mol Pharmacol. 2019 Oct;96(4):408-417. doi: 10.1124/mol.119.116806. Epub 2019 Aug 7. Mol Pharmacol. 2019. PMID: 31391291 Free PMC article.

5

Structural insights into glucocorticoid receptor function.

Frank F, Ortlund EA, Liu X. Frank F, et al. Among authors: liu x. Biochem Soc Trans. 2021 Nov 1;49(5):2333-2343. doi: 10.1042/BST20210419. Biochem Soc Trans. 2021. PMID: 34709368 Free PMC article. Review.

6

Proline-Rich Acidic Protein 1 (PRAP1) Protects the Gastrointestinal Epithelium From Irradiation-Induced Apoptosis.

Wolfarth AA, Liu X, Darby TM, Boyer DJ, Spizman JB, Owens JA, Chandrasekharan B, Naudin CR, Hanley KZ, Robinson BS, Ortlund EA, Jones RM, Neish AS. Wolfarth AA, et al. Among authors: liu x. Cell Mol Gastroenterol Hepatol. 2020;10(4):713-727. doi: 10.1016/j.jcmgh.2020.06.011. Epub 2020 Jul 3. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32629119 Free PMC article.

7

Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation.

Frank F, Liu X, Ortlund EA. Frank F, et al. Among authors: liu x. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2024685118. doi: 10.1073/pnas.2024685118. Proc Natl Acad Sci U S A. 2021. PMID: 34285072 Free PMC article.

8

Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element.

Liu X, Weikum ER, Tilo D, Vinson C, Ortlund EA. Liu X, et al. Nucleic Acids Res. 2021 Sep 7;49(15):8923-8933. doi: 10.1093/nar/gkab605. Nucleic Acids Res. 2021. PMID: 34289059 Free PMC article.

9

Evolution of androgen receptors contributes to species variation in androgenic regulation of communication signals in electric fishes.

Proffitt MR, Liu X, Ortlund EA, Smith GT. Proffitt MR, et al. Among authors: liu x. Mol Cell Endocrinol. 2023 Dec 1;578:112068. doi: 10.1016/j.mce.2023.112068. Epub 2023 Sep 14. Mol Cell Endocrinol. 2023. PMID: 37714403

10

Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment.

Liu X, Wang Y, Gutierrez JS, Damsker JM, Nagaraju K, Hoffman EP, Ortlund EA. Liu X, et al. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24285-24293. doi: 10.1073/pnas.2006890117. Epub 2020 Sep 11. Proc Natl Acad Sci U S A. 2020. PMID: 32917814 Free PMC article.

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