Shimizu R - Search Results

1

Modeling the Impact of Ensitrelvir on SARS-CoV-2 Dynamics and Its Application for Assessment of Transmission Mitigation of Patients with COVID-19.

Yamaguchi D, Saito MM, Hata A, Shimizu R, Miyazawa S, Baba T, Kubota R, Kitanishi Y. Yamaguchi D, et al. Among authors: shimizu r. Infect Dis Ther. 2024 Nov;13(11):2377-2393. doi: 10.1007/s40121-024-01046-6. Epub 2024 Oct 7. Infect Dis Ther. 2024. PMID: 39373863 Free PMC article.

2

Effect of Renal Impairment on Pharmacokinetics and Safety of Ensitrelvir, a SARS-CoV-2 3CL Protease Inhibitor.

Katsube T, Kezbor S, Shimizu R, Kubota R. Katsube T, et al. Among authors: shimizu r. Infect Dis Ther. 2024 Mar;13(3):597-607. doi: 10.1007/s40121-024-00946-x. Epub 2024 Mar 9. Infect Dis Ther. 2024. PMID: 38460082 Free PMC article.

3

Development of a SARS-CoV-2 viral dynamic model for patients with COVID-19 based on the amount of viral RNA and viral titer.

Yamaguchi D, Shimizu R, Kubota R. Yamaguchi D, et al. Among authors: shimizu r. CPT Pharmacometrics Syst Pharmacol. 2024 Aug;13(8):1354-1365. doi: 10.1002/psp4.13164. Epub 2024 May 23. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38783551 Free PMC article.

4

Safety, Tolerability, and Pharmacokinetics of the Novel Antiviral Agent Ensitrelvir Fumaric Acid, a SARS-CoV-2 3CL Protease Inhibitor, in Healthy Adults.

Shimizu R, Sonoyama T, Fukuhara T, Kuwata A, Matsuo Y, Kubota R. Shimizu R, et al. Antimicrob Agents Chemother. 2022 Oct 18;66(10):e0063222. doi: 10.1128/aac.00632-22. Epub 2022 Sep 12. Antimicrob Agents Chemother. 2022. PMID: 36094202 Free PMC article. Clinical Trial.

5

Correction to: Effect of Renal Impairment on Pharmacokinetics and Safety of Ensitrelvir, a SARS‑CoV‑2 3CL Protease Inhibitor.

Katsube T, Kezbor S, Shimizu R, Kubota R. Katsube T, et al. Among authors: shimizu r. Infect Dis Ther. 2024 Sep;13(9):2103. doi: 10.1007/s40121-024-01030-0. Infect Dis Ther. 2024. PMID: 39136875 Free PMC article. No abstract available.

6

Evaluation of Drug-Drug Interactions of Ensitrelvir, a SARS-CoV-2 3CL Protease Inhibitor, With Transporter Substrates Based on In Vitro and Clinical Studies.

Shimizu R, Matsuzaki T, Oka R, Sonoyama T, Fukuhara T, Kuwata A, Matsuo Y, Kubota R. Shimizu R, et al. J Clin Pharmacol. 2023 Aug;63(8):918-927. doi: 10.1002/jcph.2247. Epub 2023 May 10. J Clin Pharmacol. 2023. PMID: 37043676

7

Evaluation of the Drug-Drug Interaction Potential of Ensitrelvir Fumaric Acid with Cytochrome P450 3A Substrates in Healthy Japanese Adults.

Shimizu R, Sonoyama T, Fukuhara T, Kuwata A, Matsuzaki T, Matsuo Y, Kubota R. Shimizu R, et al. Clin Drug Investig. 2023 May;43(5):335-346. doi: 10.1007/s40261-023-01265-8. Epub 2023 May 12. Clin Drug Investig. 2023. PMID: 37171749 Free PMC article. Clinical Trial.

8

A Phase 1 Study of Ensitrelvir Fumaric Acid Tablets Evaluating the Safety, Pharmacokinetics and Food Effect in Healthy Adult Populations.

Shimizu R, Sonoyama T, Fukuhara T, Kuwata A, Matsuo Y, Kubota R. Shimizu R, et al. Clin Drug Investig. 2023 Oct;43(10):785-797. doi: 10.1007/s40261-023-01309-z. Epub 2023 Oct 5. Clin Drug Investig. 2023. PMID: 37798608 Free PMC article. Clinical Trial.

9

Pharmacokinetics, safety, and tolerability of single and multiple doses of zuranolone in Japanese and White healthy subjects: A phase 1 clinical trial.

Sonoyama T, Shimizu R, Kubota R, Matsuo Y, Okutsu D, Yamanaka H, Takasu K, Ogawa K, Motomiya T. Sonoyama T, et al. Among authors: shimizu r. Neuropsychopharmacol Rep. 2023 Sep;43(3):346-358. doi: 10.1002/npr2.12359. Epub 2023 Jun 27. Neuropsychopharmacol Rep. 2023. PMID: 37366077 Free PMC article. Clinical Trial.

10

Efficacy and safety of zuranolone in Japanese adults with major depressive disorder: A double-blind, randomized, placebo-controlled, phase 2 clinical trial.

Kato M, Nakagome K, Baba T, Sonoyama T, Okutsu D, Yamanaka H, Shimizu R, Motomiya T, Inoue T. Kato M, et al. Among authors: shimizu r. Psychiatry Clin Neurosci. 2023 Sep;77(9):497-509. doi: 10.1111/pcn.13569. Epub 2023 Jun 21. Psychiatry Clin Neurosci. 2023. PMID: 37252829 Free PMC article. Clinical Trial.

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