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An RNA damage response network mediates the lethality of 5-FU in colorectal cancer.
Chen JK, Merrick KA, Kong YW, Izrael-Tomasevic A, Eng G, Handly ED, Patterson JC, Cannell IG, Suarez-Lopez L, Hosios AM, Dinh A, Kirkpatrick DS, Yu K, Rose CM, Hernandez JM, Hwangbo H, Palmer AC, Vander Heiden MG, Yilmaz ÖH, Yaffe MB. Chen JK, et al. Among authors: kong yw. Cell Rep Med. 2024 Oct 15;5(10):101778. doi: 10.1016/j.xcrm.2024.101778. Epub 2024 Oct 7. Cell Rep Med. 2024. PMID: 39378883 Free PMC article.
An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types.
Chen JK, Merrick KA, Kong YW, Izrael-Tomasevic A, Eng G, Handly ED, Patterson JC, Cannell IG, Suarez-Lopez L, Hosios AM, Dinh A, Kirkpatrick DS, Yu K, Rose CM, Hernandez JM, Hwangbo H, Palmer AC, Vander Heiden MG, Yilmaz ÖH, Yaffe MB. Chen JK, et al. Among authors: kong yw. bioRxiv [Preprint]. 2023 Apr 29:2023.04.28.538590. doi: 10.1101/2023.04.28.538590. bioRxiv. 2023. Update in: Cell Rep Med. 2024 Oct 15;5(10):101778. doi: 10.1016/j.xcrm.2024.101778 PMID: 37162991 Free PMC article. Updated. Preprint.
Inducing DNA damage through R-loops to kill cancer cells.
Lam FC, Kong YW, Yaffe MB. Lam FC, et al. Among authors: kong yw. Mol Cell Oncol. 2020 Nov 20;8(1):1848233. doi: 10.1080/23723556.2020.1848233. Mol Cell Oncol. 2020. PMID: 33553604 Free PMC article.
Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints.
Kong YW, Dreaden EC, Morandell S, Zhou W, Dhara SS, Sriram G, Lam FC, Patterson JC, Quadir M, Dinh A, Shopsowitz KE, Varmeh S, Yilmaz ÖH, Lippard SJ, Reinhardt HC, Hemann MT, Hammond PT, Yaffe MB. Kong YW, et al. Nat Commun. 2020 Aug 17;11(1):4124. doi: 10.1038/s41467-020-17958-z. Nat Commun. 2020. PMID: 32807787 Free PMC article.
RNA-Peptide nanoplexes drug DNA damage pathways in high-grade serous ovarian tumors.
Dreaden EC, Kong YW, Quadir MA, Correa S, Suárez-López L, Barberio AE, Hwang MK, Shi AC, Oberlton B, Gallagher PN, Shopsowitz KE, Elias KM, Yaffe MB, Hammond PT. Dreaden EC, et al. Among authors: kong yw. Bioeng Transl Med. 2018 Jan 19;3(1):26-36. doi: 10.1002/btm2.10086. eCollection 2018 Jan. Bioeng Transl Med. 2018. PMID: 29376131 Free PMC article.
41 results