Romanelli MM - Search Results

1

Synthesis of a dehydrodieugenol B derivative as a lead compound for visceral leishmaniasis-mechanism of action and in vivo pharmacokinetic studies.

Amaral M, Romanelli MM, Asiki H, Bicker J, Lage DP, Freitas CS, Taniwaki NN, Lago JHG, Coelho EAF, Falcão A, Fortuna A, Anderson EA, Tempone AG. Amaral M, et al. Among authors: romanelli mm. Antimicrob Agents Chemother. 2024 Nov 6;68(11):e0083124. doi: 10.1128/aac.00831-24. Epub 2024 Oct 9. Antimicrob Agents Chemother. 2024. PMID: 39382276 Free PMC article.

2

Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study.

Ferreira DD, Mesquita JT, da Costa Silva TA, Romanelli MM, da Gama Jaen Batista D, da Silva CF, da Gama ANS, Neves BJ, Melo-Filho CC, Correia Soeiro MN, Andrade CH, Tempone AG. Ferreira DD, et al. Among authors: romanelli mm. J Venom Anim Toxins Incl Trop Dis. 2018 Oct 30;24:30. doi: 10.1186/s40409-018-0165-8. eCollection 2018. J Venom Anim Toxins Incl Trop Dis. 2018. PMID: 30450114 Free PMC article.

3

Antitrypanosomal Activity of Acetogenins Isolated from the Seeds of Porcelia macrocarpa Is Associated with Alterations in Both Plasma Membrane Electric Potential and Mitochondrial Membrane Potential.

Oliveira EA, Brito IA, Lima ML, Romanelli M, Moreira-Filho JT, Neves BJ, Andrade CH, Sartorelli P, Tempone AG, Costa-Silva TA, Lago JHG. Oliveira EA, et al. J Nat Prod. 2019 May 24;82(5):1177-1182. doi: 10.1021/acs.jnatprod.8b00890. Epub 2019 May 2. J Nat Prod. 2019. PMID: 31046273

4

Antitrypanosomal activity of isololiolide isolated from the marine hydroid Macrorhynchia philippina (Cnidaria, Hydrozoa).

Lima ML, Romanelli MM, Borborema SET, Johns DM, Migotto AE, Lago JHG, Tempone AG. Lima ML, et al. Among authors: romanelli mm. Bioorg Chem. 2019 Aug;89:103002. doi: 10.1016/j.bioorg.2019.103002. Epub 2019 May 20. Bioorg Chem. 2019. PMID: 31136901

5

Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis.

Romanelli MM, da Costa-Silva TA, Cunha-Junior E, Dias Ferreira D, Guerra JM, Galisteo AJ Jr, Pinto EG, Barbosa LRS, Torres-Santos EC, Tempone AG. Romanelli MM, et al. Front Cell Infect Microbiol. 2019 Oct 29;9:353. doi: 10.3389/fcimb.2019.00353. eCollection 2019. Front Cell Infect Microbiol. 2019. PMID: 31737574 Free PMC article.

6

Calanolides E1 and E2, two related coumarins from Calophyllum brasiliense Cambess. (Clusiaceae), displayed in vitro activity against amastigote forms of Trypanosoma cruzi and Leishmania infantum.

Silva LG, Gomes KS, Costa-Silva TA, Romanelli MM, Tempone AG, Sartorelli P, Lago JHG. Silva LG, et al. Among authors: romanelli mm. Nat Prod Res. 2021 Dec;35(23):5373-5377. doi: 10.1080/14786419.2020.1765347. Epub 2020 May 22. Nat Prod Res. 2021. PMID: 32441133

7

Repurposing topical triclosan for cutaneous leishmaniasis: Preclinical efficacy in a murine Leishmania (L.) amazonensis model.

Mesquita JT, Romanelli MM, de Melo Trinconi Trinconi Cm C, Guerra JM, Taniwaki NN, Uliana SRB, Reimão JQ, Tempone AG. Mesquita JT, et al. Among authors: romanelli mm. Drug Dev Res. 2022 Apr;83(2):285-295. doi: 10.1002/ddr.21725. Epub 2020 Aug 6. Drug Dev Res. 2022. PMID: 32767443

8

Synthesis and Structure-Activity Relationship of Dehydrodieugenol B Neolignans against Trypanosoma cruzi.

Sear CE, Pieper P, Amaral M, Romanelli MM, Costa-Silva TA, Haugland MM, Tate JA, Lago JHG, Tempone AG, Anderson EA. Sear CE, et al. Among authors: romanelli mm. ACS Infect Dis. 2020 Nov 13;6(11):2872-2878. doi: 10.1021/acsinfecdis.0c00523. Epub 2020 Oct 13. ACS Infect Dis. 2020. PMID: 33047947 Free PMC article.

9

Optimization of physicochemical properties is a strategy to improve drug-likeness associated with activity: Novel active and selective compounds against Trypanosoma cruzi.

Varela MT, Amaral M, Romanelli MM, de Castro Levatti EV, Tempone AG, Fernandes JPS. Varela MT, et al. Among authors: romanelli mm. Eur J Pharm Sci. 2022 Apr 1;171:106114. doi: 10.1016/j.ejps.2021.106114. Epub 2022 Jan 2. Eur J Pharm Sci. 2022. PMID: 34986415 Free article.

10

Antileishmanial Effects of Acetylene Acetogenins from Seeds of Porcelia macrocarpa (Warm.) R.E. Fries (Annonaceae) and Semisynthetic Derivatives.

Brito IA, Thevenard F, Costa-Silva TA, Oliveira SS, Cunha RLOR, de Oliveira EA, Sartorelli P, Guadagnin RC, Romanelli MM, Tempone AG, Lago JHG. Brito IA, et al. Among authors: romanelli mm. Molecules. 2022 Jan 28;27(3):893. doi: 10.3390/molecules27030893. Molecules. 2022. PMID: 35164158 Free PMC article.

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