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Page 1
A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis.
Li R, Colombo M, Wang G, Rodriguez-Romera A, Benlabiod C, Jooss NJ, O'Sullivan J, Brierley CK, Clark SA, Pérez Sáez JM, Fernández PA, Schoof EM, Porse B, Meng Y, Khan AO, Wen S, Dong P, Zhou W, Sousos N, Murphy L, Clarke M, Olijnik AA, Wong ZC, Karali CS, Sirinukunwattana K, Ryou H, Norfo R, Cheng Q, Carrelha J, Ren Z, Thongjuea S, Rathinam VA, Krishnan A, Royston D, Rabinovich GA, Mead AJ, Psaila B. Li R, et al. Among authors: karali cs. Sci Transl Med. 2024 Oct 9;16(768):eadj7552. doi: 10.1126/scitranslmed.adj7552. Epub 2024 Oct 9. Sci Transl Med. 2024. PMID: 39383242 Free PMC article.
Rapamycin Treatment Reduces Brain Pericyte Constriction in Ischemic Stroke.
Beard DJ, Brown LS, Morris GP, Couch Y, Adriaanse BA, Karali CS, Schneider AM, Howells DW, Redzic ZB, Sutherland BA, Buchan AM. Beard DJ, et al. Among authors: karali cs. Transl Stroke Res. 2024 Sep 27. doi: 10.1007/s12975-024-01298-x. Online ahead of print. Transl Stroke Res. 2024. PMID: 39331260
Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies.
Khan AO, Rodriguez-Romera A, Reyat JS, Olijnik AA, Colombo M, Wang G, Wen WX, Sousos N, Murphy LC, Grygielska B, Perrella G, Mahony CB, Ling RE, Elliott NE, Karali CS, Stone AP, Kemble S, Cutler EA, Fielding AK, Croft AP, Bassett D, Poologasundarampillai G, Roy A, Gooding S, Rayes J, Machlus KR, Psaila B. Khan AO, et al. Among authors: karali cs. Cancer Discov. 2023 Feb 6;13(2):364-385. doi: 10.1158/2159-8290.CD-22-0199. Cancer Discov. 2023. PMID: 36351055 Free PMC article.
Epigenetic potentiation of somatostatin-2 by guadecitabine in neuroendocrine neoplasias as a novel method to allow delivery of peptide receptor radiotherapy.
Evans JS, Beaumont J, Braga M, Masrour N, Mauri F, Beckley A, Butt S, Karali CS, Cawthorne C, Archibald S, Aboagye EO, Sharma R. Evans JS, et al. Among authors: karali cs. Eur J Cancer. 2022 Nov;176:110-120. doi: 10.1016/j.ejca.2022.09.009. Epub 2022 Oct 5. Eur J Cancer. 2022. PMID: 36208569 Free article.
Impaired antibody response to COVID-19 vaccination in patients with chronic myeloid neoplasms.
Chowdhury O, Bruguier H, Mallett G, Sousos N, Crozier K, Allman C, Eyre D, Lumley S, Strickland M, Karali CS, Murphy L, Sternberg A, Jeffery K, Mead AJ, Peniket A, Psaila B. Chowdhury O, et al. Among authors: karali cs. Br J Haematol. 2021 Sep;194(6):1010-1015. doi: 10.1111/bjh.17644. Epub 2021 Jun 24. Br J Haematol. 2021. PMID: 34132395 Free PMC article. Clinical Trial. No abstract available.
A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models.
Zarghami N, Soto MS, Perez-Balderas F, Khrapitchev AA, Karali CS, Johanssen VA, Ansorge O, Larkin JR, Sibson NR. Zarghami N, et al. Among authors: karali cs. J Cereb Blood Flow Metab. 2021 Jul;41(7):1592-1607. doi: 10.1177/0271678X20968943. Epub 2020 Nov 5. J Cereb Blood Flow Metab. 2021. PMID: 33153376 Free PMC article.