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Cellular senescence by loss of Men1 in osteoblasts is critical for age-related osteoporosis.
Ukon Y, Kaito T, Hirai H, Kitahara T, Bun M, Kodama J, Tateiwa D, Nakagawa S, Ikuta M, Furuichi T, Kanie Y, Fujimori T, Takenaka S, Yamamuro T, Otsuru S, Okada S, Yamashita M, Imamura T. Ukon Y, et al. Among authors: hirai h. Aging Cell. 2024 Oct;23(10):e14254. doi: 10.1111/acel.14254. Epub 2024 Jun 22. Aging Cell. 2024. PMID: 39384404 Free PMC article.
Selective Retinoic Acid Receptor γ Antagonist 7C is a Potent Enhancer of BMP-Induced Ectopic Endochondral Bone Formation.
Tateiwa D, Kaito T, Hashimoto K, Okada R, Kodama J, Kushioka J, Bal Z, Tsukazaki H, Nakagawa S, Ukon Y, Hirai H, Tian H, Alferiev I, Chorny M, Otsuru S, Okada S, Iwamoto M. Tateiwa D, et al. Among authors: hirai h. Front Cell Dev Biol. 2022 Mar 14;10:802699. doi: 10.3389/fcell.2022.802699. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35359440 Free PMC article.
Prostaglandin EP4 Selective Agonist AKDS001 Enhances New Bone Formation by Minimodeling in a Rat Heterotopic Xenograft Model of Human Bone.
Ukon Y, Nishida M, Yamamori N, Takeyama K, Sakamoto K, Takenaka S, Makino T, Fujimori T, Sakai Y, Kanie Y, Kodama J, Bal Z, Tateiwa D, Nakagawa S, Hirai H, Okada S, Kaito T. Ukon Y, et al. Among authors: hirai h. Front Bioeng Biotechnol. 2022 Mar 17;10:845716. doi: 10.3389/fbioe.2022.845716. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 35372320 Free PMC article.
A synthetic retinoic acid receptor γ antagonist (7C)-loaded nanoparticle enhances bone morphogenetic protein-induced bone regeneration in a rat spinal fusion model.
Tateiwa D, Iwamoto M, Kodama J, Ukon Y, Hirai H, Ikuta M, Kitahara T, Furuichi T, Bun M, Otsuru S, Okada S, Kaito T. Tateiwa D, et al. Among authors: hirai h. Spine J. 2024 May;24(5):899-908. doi: 10.1016/j.spinee.2023.11.021. Epub 2023 Dec 12. Spine J. 2024. PMID: 38092193 Free PMC article.
rhBMP-2-loaded hydroxyapatite/beta-tricalcium phosphate microsphere/hydrogel composite promotes bone regeneration in a novel rat femoral nonunion model.
Kitahara T, Tateiwa D, Hirai H, Ikuta M, Furuichi T, Bun M, Ukon Y, Kanie Y, Furuya M, Fujimori T, Okada S, Kaito T. Kitahara T, et al. Among authors: hirai h. Front Bioeng Biotechnol. 2024 Oct 7;12:1461260. doi: 10.3389/fbioe.2024.1461260. eCollection 2024. Front Bioeng Biotechnol. 2024. PMID: 39434714 Free PMC article.
A Model for Decoding Resistance in Precision Oncology: Acquired Resistance to FGFR inhibitors in Cholangiocarcinoma.
Goyal L, DiToro D, Facchinetti F, Martin EE, Peng P, Baiev I, Iyer R, Maurer J, Reyes S, Zhang K, Majeed U, Berchuck JE, Chen CT, Walmsley C, Pinto C, Vasseur D, Gordan JD, Mody K, Borad M, Karasic T, Damjanov N, Danysh BP, Wehrenberg-Klee E, Kambadakone AR, Saha SK, Hoffman ID, Nelson KJ, Iyer S, Qiang X, Sun C, Wang H, Li L, Javle M, Lin B, Harris W, Zhu AX, Cleary JM, Flaherty KT, Harris T, Shroff RT, Leshchiner I, Parida L, Kelley RK, Fan J, Stone JR, Uboha NV, Hirai H, Sootome H, Wu F, Bensen DC, Hollebecque A, Friboulet L, Lennerz JK, Getz G, Juric D. Goyal L, et al. Among authors: hirai h. Ann Oncol. 2024 Dec 18:S0923-7534(24)04990-1. doi: 10.1016/j.annonc.2024.12.011. Online ahead of print. Ann Oncol. 2024. PMID: 39706336 Free article.
1,860 results