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AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution.
Schade AE, Perurena N, Yang Y, Rodriguez CL, Krishnan A, Gardner A, Loi P, Xu Y, Nguyen VTM, Mastellone GM, Pilla NF, Watanabe M, Ota K, Davis RA, Mattioli K, Xiang D, Zoeller JJ, Lin JR, Morganti S, Garrido-Castro AC, Tolaney SM, Li Z, Barbie DA, Sorger PK, Helin K, Santagata S, Knott SRV, Cichowski K. Schade AE, et al. Among authors: li z. Nature. 2024 Nov;635(8039):755-763. doi: 10.1038/s41586-024-08031-6. Epub 2024 Oct 9. Nature. 2024. PMID: 39385030 Free PMC article.
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