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SARS-CoV-2 variant replacement constrains vaccine-specific viral diversification.
Dearlove BL, Fries AC, Epsi NJ, Richard SA, Ganesan A, Huprikar N, Lindholm DA, Mende K, Colombo RE, Colombo C, Bai H, Larson DT, Ewers EC, Lalani T, Smith AG, Berjohn CM, Maves RC, Jones MU, Saunders D, Maldonado CJ, Mody RM, Bazan SE, Tribble DR, Burgess T, Simons MP, Agan BK, Pollett SD, Rolland M. Dearlove BL, et al. Among authors: bai h. Virus Evol. 2024 Sep 2;10(1):veae071. doi: 10.1093/ve/veae071. eCollection 2024. Virus Evol. 2024. PMID: 39386074 Free PMC article.
A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants.
Dearlove B, Lewitus E, Bai H, Li Y, Reeves DB, Joyce MG, Scott PT, Amare MF, Vasan S, Michael NL, Modjarrad K, Rolland M. Dearlove B, et al. Among authors: bai h. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23652-23662. doi: 10.1073/pnas.2008281117. Epub 2020 Aug 31. Proc Natl Acad Sci U S A. 2020. PMID: 32868447 Free PMC article.
HIV-1 infections with multiple founders associate with the development of neutralization breadth.
Lewitus E, Townsley SM, Li Y, Donofrio GC, Dearlove BL, Bai H, Sanders-Buell E, O'Sullivan AM, Bose M, Kibuuka H, Maganga L, Nitayaphan S, Sawe FK, Eller LA, Michael NL, Polonis VR, Ake JA, Vasan S, Robb ML, Tovanabutra S, Krebs SJ, Rolland M. Lewitus E, et al. Among authors: bai h. PLoS Pathog. 2022 Mar 18;18(3):e1010369. doi: 10.1371/journal.ppat.1010369. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35303045 Free PMC article.
A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein.
Joyce MG, Sankhala RS, Chen WH, Choe M, Bai H, Hajduczki A, Yan L, Sterling SL, Peterson CE, Green EC, Smith C, de Val N, Amare M, Scott P, Laing ED, Broder CC, Rolland M, Michael NL, Modjarrad K. Joyce MG, et al. Among authors: bai h. bioRxiv [Preprint]. 2020 Mar 17:2020.03.15.992883. doi: 10.1101/2020.03.15.992883. bioRxiv. 2020. PMID: 32511298 Free PMC article. Preprint.
Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features.
Magaret CA, Li L, deCamp AC, Rolland M, Juraska M, Williamson BD, Ludwig J, Molitor C, Benkeser D, Luedtke A, Simpkins B, Heng F, Sun Y, Carpp LN, Bai H, Dearlove BL, Giorgi EE, Jongeneelen M, Brandenburg B, McCallum M, Bowen JE, Veesler D, Sadoff J, Gray GE, Roels S, Vandebosch A, Stieh DJ, Le Gars M, Vingerhoets J, Grinsztejn B, Goepfert PA, de Sousa LP, Silva MST, Casapia M, Losso MH, Little SJ, Gaur A, Bekker LG, Garrett N, Truyers C, Van Dromme I, Swann E, Marovich MA, Follmann D, Neuzil KM, Corey L, Greninger AL, Roychoudhury P, Hyrien O, Gilbert PB. Magaret CA, et al. Among authors: bai h. Nat Commun. 2024 Mar 11;15(1):2175. doi: 10.1038/s41467-024-46536-w. Nat Commun. 2024. PMID: 38467646 Free PMC article.
RV144 vaccine imprinting constrained HIV-1 evolution following breakthrough infection.
Lewitus E, Sanders-Buell E, Bose M, O'Sullivan AM, Poltavee K, Li Y, Bai H, Mdluli T, Donofrio G, Slike B, Zhao H, Wong K, Chen L, Miller S, Lee J, Ahani B, Lepore S, Muhammad S, Grande R, Tran U, Dussupt V, Mendez-Rivera L, Nitayaphan S, Kaewkungwal J, Pitisuttithum P, Rerks-Ngarm S, O'Connell RJ, Janes H, Gilbert PB, Gramzinski R, Vasan S, Robb ML, Michael NL, Krebs SJ, Herbeck JT, Edlefsen PT, Mullins JI, Kim JH, Tovanabutra S, Rolland M. Lewitus E, et al. Among authors: bai h. Virus Evol. 2021 Jul 9;7(2):veab057. doi: 10.1093/ve/veab057. eCollection 2021. Virus Evol. 2021. PMID: 34532060 Free PMC article.
4,903 results