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151 results

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Page 1
Alternative splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and tumor progression in ovarian cancer.
Javed Z, Shin DH, Pan W, White SR, Kim YS, Elhaw AT, Kamlapurkar S, Cheng YY, Benson JC, Abdelnaby AE, Phaëton R, Wang HG, Yang S, Sullivan MLG, St Croix CM, Watkins SC, Mullett SJ, Gelhaus SL, Lee N, Coffman LG, Aird KM, Trebak M, Mythreye K, Walter V, Hempel N. Javed Z, et al. Among authors: st croix cm. bioRxiv [Preprint]. 2024 Jan 24:2023.09.20.558501. doi: 10.1101/2023.09.20.558501. bioRxiv. 2024. Update in: EMBO Rep. 2024 Oct;25(10):4281-4310. doi: 10.1038/s44319-024-00232-4 PMID: 37790404 Free PMC article. Updated. Preprint.
Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension.
Harvey LD, Alotaibi M, Kim HJ, Tai YY, Tang Y, Sun W, El Khoury W, Woodcock CC, Aaraj YA, St Croix CM, Stolz DB, Lee J, Cheng MH, Schwantes-An TH, Desai AA, Pauciulo MW, Nichols WC, Webb A, Lafyatis R, Nouraie M, Wu H, McDonald JG, Chauvet C, Cheng S, Bahar I, Bertero T, Benza RL, Jain M, Chan SY. Harvey LD, et al. Among authors: st croix cm. bioRxiv [Preprint]. 2024 Mar 1:2024.02.26.582142. doi: 10.1101/2024.02.26.582142. bioRxiv. 2024. PMID: 38464060 Free PMC article. Preprint.
Lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension.
Harvey LD, Alotaibi M, Tai YY, Tang Y, Kim HJ, Kelly NJ, Sun W, Woodcock CC, Arshad S, Culley MK, El Khoury W, Xie R, Al Aaraj Y, Zhao J, Hafeez N, Rao RJ, Jiang S, Negi V, Kirillova A, Perk D, Watson AM, St Croix CM, Stolz DB, Lee JY, Cheng MH, Zhang M, Detmer S, Guzman E, Manan RS, Saggar R, Haley KJ, Waxman AB, Okawa S, Schwantes-An TH, Pauciulo MW, Wang B, Webb A, Chauvet C, Anderson DG, Nichols WC, Desai AA, Lafyatis R, Nouraie SM, Wu H, McDonald JG, Cheng S, Bahar I, Bertero T, Benza RL, Jain M, Chan SY. Harvey LD, et al. Among authors: st croix cm. Science. 2025 Jan 24;387(6732):eadn7277. doi: 10.1126/science.adn7277. Epub 2025 Jan 24. Science. 2025. PMID: 39847635
Menopause-induced 17β-estradiol and progesterone loss increases senescence markers, matrix disassembly and degeneration in mouse cartilage.
Gilmer G, Iijima H, Hettinger ZR, Jackson N, Bergmann J, Bean AC, Shahshahan N, Creed E, Kopchak R, Wang K, Houston H, Franks JM, Calderon MJ, St Croix C, Thurston RC, Evans CH, Ambrosio F. Gilmer G, et al. Among authors: st croix c. Nat Aging. 2025 Jan;5(1):65-86. doi: 10.1038/s43587-024-00773-2. Epub 2025 Jan 16. Nat Aging. 2025. PMID: 39820791
Drp1 splice variants regulate ovarian cancer mitochondrial dynamics and tumor progression.
Javed Z, Shin DH, Pan W, White SR, Elhaw AT, Kim YS, Kamlapurkar S, Cheng YY, Benson JC, Abdelnaby AE, Phaëton R, Wang HG, Yang S, Sullivan MLG, St Croix CM, Watkins SC, Mullett SJ, Gelhaus SL, Lee N, Coffman LG, Aird KM, Trebak M, Mythreye K, Walter V, Hempel N. Javed Z, et al. Among authors: st croix cm. EMBO Rep. 2024 Oct;25(10):4281-4310. doi: 10.1038/s44319-024-00232-4. Epub 2024 Aug 27. EMBO Rep. 2024. PMID: 39191946 Free PMC article.
Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer.
Frisbie L, Pressimone C, Dyer E, Baruwal R, Garcia G, St Croix C, Watkins S, Calderone M, Gorecki G, Javed Z, Atiya HI, Hempel N, Pearson A, Coffman LG. Frisbie L, et al. Among authors: st croix c. Cell Rep. 2024 Aug 27;43(8):114551. doi: 10.1016/j.celrep.2024.114551. Epub 2024 Jul 26. Cell Rep. 2024. PMID: 39067022 Free PMC article.
Compartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes.
Yamada K, St Croix C, Stolz DB, Tyurina YY, Tyurin VA, Bradley LR, Kapralov AA, Deng Y, Zhou X, Wei Q, Liao B, Fukuda N, Sullivan M, Trudeau J, Ray A, Kagan VE, Zhao J, Wenzel SE. Yamada K, et al. Among authors: st croix c. Nat Commun. 2024 Jul 10;15(1):5818. doi: 10.1038/s41467-024-50222-2. Nat Commun. 2024. PMID: 38987265 Free PMC article.
151 results