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Page 1
TNFSF13 insufficiency disrupts human colonic epithelial cell-mediated B cell differentiation.
Ma X, Dawany N, Kondo A, Maurer K, Karakasheva T, Shraim R, Williams PA, Parham LR, Simon LA, Danan CH, Conrad MA, Piccoli DA, Devoto M, Sullivan KE, Kaestner KH, Kelsen JR, Hamilton KE. Ma X, et al. Among authors: hamilton ke. bioRxiv [Preprint]. 2024 Sep 23:2024.09.23.614260. doi: 10.1101/2024.09.23.614260. bioRxiv. 2024. PMID: 39386555 Free PMC article. Preprint.
Intestinal transit amplifying cells require METTL3 for growth factor signaling, KRAS expression, and cell survival.
Danan CH, Naughton KE, Hayer KE, Vellappan S, McMillan EA, Zhou Y, Matsuda R, Nettleford SK, Katada K, Parham LR, Ma X, Chowdhury A, Wilkins BJ, Shah P, Weitzman MD, Hamilton KE. Danan CH, et al. Among authors: hamilton ke. bioRxiv [Preprint]. 2023 Apr 21:2023.04.06.535853. doi: 10.1101/2023.04.06.535853. bioRxiv. 2023. Update in: JCI Insight. 2023 Dec 8;8(23):e171657. doi: 10.1172/jci.insight.171657 PMID: 37066277 Free PMC article. Updated. Preprint.
Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis.
Sasaki M, Hara T, Wang JX, Zhou Y, Kennedy KV, Umeweni NN, Alston MA, Spergel ZC, Nakagawa R, Mcmillan EA, Whelan KA, Karakasheva TA, Hamilton KE, Ruffner MA, Muir AB. Sasaki M, et al. Among authors: hamilton ke. bioRxiv [Preprint]. 2023 Mar 28:2023.03.27.534387. doi: 10.1101/2023.03.27.534387. bioRxiv. 2023. Update in: Cell Mol Gastroenterol Hepatol. 2024;17(6):923-937. doi: 10.1016/j.jcmgh.2024.01.025 PMID: 37034590 Free PMC article. Updated. Preprint.
Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Genes.
Kelsen JR, Dawany N, Conrad MA, Karakasheva TA, Maurer K, Wei JM, Uman S, Dent MH, Behera R, Bryant LM, Ma X, Moreira L, Chatterji P, Shraim R, Merz A, Mizuno R, Simon LA, Muir AB, Giraudo C, Behrens EM, Whelan KA, Devoto M, Russo PA, Andres SF, Sullivan KE, Hamilton KE. Kelsen JR, et al. Among authors: hamilton ke. Inflamm Bowel Dis. 2021 Jan 19;27(2):256-267. doi: 10.1093/ibd/izaa145. Inflamm Bowel Dis. 2021. PMID: 32556182 Free PMC article.
Autophagy contributes to homeostasis in esophageal epithelium where high autophagic vesicle content marks basal cells with limited proliferation and enhanced self-renewal potential.
Klochkova A, Karami AL, Fuller AD, Parham LR, Panchani SR, Natarajan S, Jackson JL, Mu A, Tan Y, Cai KQ, Klein-Szanto AJ, Muir AB, Tétreault MP, Hamilton KE, Whelan KA. Klochkova A, et al. Among authors: hamilton ke. bioRxiv [Preprint]. 2023 Sep 22:2023.09.20.558614. doi: 10.1101/2023.09.20.558614. bioRxiv. 2023. Update in: Cell Mol Gastroenterol Hepatol. 2024;18(1):15-40. doi: 10.1016/j.jcmgh.2024.02.018 PMID: 37781581 Free PMC article. Updated. Preprint.
Intestinal epithelial autophagy is required for the regenerative benefit of calorie restriction.
Williams PA, Naughton KE, Simon LA, Soto GE, Parham LR, Ma X, Danan CH, Hu W, Friedman ES, McMillan EA, Mehta H, Stoltz MA, Ocaña JS, Zackular JP, Bittinger K, Whelan KA, Karakasheva TA, Hamilton KE. Williams PA, et al. Among authors: hamilton ke. Am J Physiol Gastrointest Liver Physiol. 2023 May 1;324(5):G354-G368. doi: 10.1152/ajpgi.00248.2022. Epub 2023 Feb 28. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 36852920 Free PMC article.
IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B.
Parham LR, Williams PA, Katada K, Nettleford SK, Chatterji P, Acheampong KK, Danan CH, Ma X, Simon LA, Naughton KE, Mizuno R, Karakasheva T, McMillan EA, Whelan KA, Brady DC, Shaffer SM, Hamilton KE. Parham LR, et al. Among authors: hamilton ke. Cell Mol Gastroenterol Hepatol. 2024;17(3):439-451. doi: 10.1016/j.jcmgh.2023.12.001. Epub 2023 Dec 9. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38081361 Free PMC article.
Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP1/IGF2BP1.
Chatterji P, Williams PA, Whelan KA, Samper FC, Andres SF, Simon LA, Parham LR, Mizuno R, Lundsmith ET, Lee DS, Liang S, Wijeratne HS, Marti S, Chau L, Giroux V, Wilkins BJ, Wu GD, Shah P, Tartaglia GG, Hamilton KE. Chatterji P, et al. Among authors: hamilton ke. EMBO Rep. 2019 Jun;20(6):e47074. doi: 10.15252/embr.201847074. Epub 2019 May 6. EMBO Rep. 2019. PMID: 31061170 Free PMC article.
Spatial transcriptomics add a new dimension to our understanding of the gut.
Danan CH, Katada K, Parham LR, Hamilton KE. Danan CH, et al. Among authors: hamilton ke. Am J Physiol Gastrointest Liver Physiol. 2023 Feb 1;324(2):G91-G98. doi: 10.1152/ajpgi.00191.2022. Epub 2022 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 36472345 Free PMC article. Review.
RNA regulons are essential in intestinal homeostasis.
Parham LR, Williams PA, Chatterji P, Whelan KA, Hamilton KE. Parham LR, et al. Among authors: hamilton ke. Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G197-G204. doi: 10.1152/ajpgi.00403.2017. Epub 2018 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30520692 Free PMC article. Review.
76 results