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Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells.
Uguen M, Shell DJ, Silva M, Deng Y, Li F, Szewczyk MM, Yang K, Zhao Y, Stashko MA, Norris-Drouin JL, Waybright JM, Beldar S, Rectenwald JM, Mordant AL, Webb TS, Herring LE, Arrowsmith CH, Ackloo S, Gygi SP, McGinty RK, Barsyte-Lovejoy D, Liu P, Halabelian L, James LI, Pearce KH, Frye SV. Uguen M, et al. Among authors: deng y. bioRxiv [Preprint]. 2024 Sep 28:2024.09.27.615363. doi: 10.1101/2024.09.27.615363. bioRxiv. 2024. PMID: 39386588 Free PMC article. Preprint.
SETDB1 Triple Tudor Domain Ligand, ( R,R )-59, Promotes Methylation of Akt1 in Cells.
Uguen M, Deng Y, Li F, Shell DJ, Norris-Drouin JL, Stashko MA, Ackloo S, Arrowsmith CH, James LI, Liu P, Pearce KH, Frye SV. Uguen M, et al. Among authors: deng y. bioRxiv [Preprint]. 2023 May 10:2023.05.10.539986. doi: 10.1101/2023.05.10.539986. bioRxiv. 2023. Update in: ACS Chem Biol. 2023 Aug 18;18(8):1846-1853. doi: 10.1021/acschembio.3c00280 PMID: 37214894 Free PMC article. Updated. Preprint.
Rice transcription factor bHLH25 confers resistance to multiple diseases by sensing H2O2.
Liao H, Fang Y, Yin J, He M, Wei Y, Zhang J, Yong S, Cha J, Song L, Zhu X, Chen X, Kováč J, Hou Q, Ma Z, Zhou X, Chen L, Yumoto E, Yang T, He Q, Li W, Deng Y, Li H, Li M, Qing H, Zou L, Bi Y, Liu J, Yang Y, Ye D, Tao Q, Wang L, Xiong Q, Lu X, Tang Y, Li T, Ma B, Qin P, Li Y, Wang W, Qian Y, Ďurkovič J, Miyamoto K, Chern M, Li S, Li W, Wang J, Chen X. Liao H, et al. Among authors: deng y. Cell Res. 2025 Jan 14. doi: 10.1038/s41422-024-01058-4. Online ahead of print. Cell Res. 2025. PMID: 39806170
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