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Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke.
Wei C, Xiao Z, Zhang Y, Luo Z, Liu D, Hu L, Shen D, Liu M, Shi L, Wang X, Lan T, Dai Q, Liu J, Chen W, Zhang Y, Sun Q, Wu W, Wang P, Zhang C, Hu J, Wang C, Yang F, Li Q. Wei C, et al. Among authors: hu j, hu l. Cell Death Differ. 2024 Aug;31(8):983-998. doi: 10.1038/s41418-024-01303-8. Epub 2024 May 8. Cell Death Differ. 2024. PMID: 38719928
A Class of Disulfide Compounds Suppresses Ferroptosis by Stabilizing GPX4.
Liu JP, Cen SY, Xue Z, Wang TX, Gao Y, Zheng J, Zhang C, Hu J, Nie S, Xiong Y, Guan KL, Yuan HX. Liu JP, et al. Among authors: hu j. ACS Chem Biol. 2022 Dec 16;17(12):3389-3406. doi: 10.1021/acschembio.2c00445. Epub 2022 Nov 29. ACS Chem Biol. 2022. PMID: 36446024
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