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In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model.
Silva JM, Zupancic E, Vandermeulen G, Oliveira VG, Salgado A, Videira M, Gaspar M, Graca L, Préat V, Florindo HF. Silva JM, et al. J Control Release. 2015 Jan 28;198:91-103. doi: 10.1016/j.jconrel.2014.11.033. Epub 2014 Dec 5. J Control Release. 2015. PMID: 25483429
Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment.
Acúrcio RC, Pozzi S, Carreira B, Pojo M, Gómez-Cebrián N, Casimiro S, Fernandes A, Barateiro A, Farricha V, Brito J, Leandro AP, Salvador JAR, Graça L, Puchades-Carrasco L, Costa L, Satchi-Fainaro R, Guedes RC, Florindo HF. Acúrcio RC, et al. J Immunother Cancer. 2022 Jul;10(7):e004695. doi: 10.1136/jitc-2022-004695. J Immunother Cancer. 2022. PMID: 35863821 Free PMC article.
Polyoxazoline-Based Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and Anti-PD-1 Immunotherapy against Solid Tumors.
Matos AI, Peres C, Carreira B, Moura LIF, Acúrcio RC, Vogel T, Wegener E, Ribeiro F, Afonso MB, Santos FMF, Martínez-Barriocanal Á, Arango D, Viana AS, Góis PMP, Silva LC, Rodrigues CMP, Graca L, Jordan R, Satchi-Fainaro R, Florindo HF. Matos AI, et al. Among authors: florindo hf. Adv Sci (Weinh). 2023 Sep;10(25):e2300299. doi: 10.1002/advs.202300299. Epub 2023 Jul 11. Adv Sci (Weinh). 2023. PMID: 37434063 Free PMC article.
Specialized Tfh cell subsets driving type-1 and type-2 humoral responses in lymphoid tissue.
Kumar S, Basto AP, Ribeiro F, Almeida SCP, Campos P, Peres C, Pulvirenti N, Al-Khalidi S, Kilbey A, Tosello J, Piaggio E, Russo M, Gama-Carvalho M, Coffelt SB, Roberts EW, Geginat J, Florindo HF, Graca L. Kumar S, et al. Among authors: florindo hf. Cell Discov. 2024 Jun 4;10(1):64. doi: 10.1038/s41421-024-00681-0. Cell Discov. 2024. PMID: 38834551 Free PMC article.
60 results