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34 results

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Page 1
Tumor-derived CCL2 drives tumor growth and immunosuppression in IDH1-mutant cholangiocarcinoma.
Zabransky DJ, Kartalia E, Lee JW, Leatherman JM, Charmsaz S, Young SE, Chhabra Y, Franch-Expósito S, Kang M, Maru S, Rastkari N, Davis M, Dalton WB, Oshima K, Baretti M, Azad NS, Jaffee EM, Yarchoan M. Zabransky DJ, et al. Among authors: charmsaz s. Hepatology. 2024 Dec 3. doi: 10.1097/HEP.0000000000001185. Online ahead of print. Hepatology. 2024. PMID: 39626209
Entinostat in combination with nivolumab in metastatic pancreatic ductal adenocarcinoma: a phase 2 clinical trial.
Baretti M, Danilova L, Durham JN, Betts CB, Cope L, Sidiropoulos DN, Tandurella JA, Charmsaz S, Gross N, Hernandez A, Ho WJ, Thoburn C, Walker R, Leatherman J, Mitchell S, Christmas B, Saeed A, Gaykalova DA, Yegnasubramanian S, Fertig EJ, Coussens LM, Yarchoan M, Jaffee E, Azad NS. Baretti M, et al. Among authors: charmsaz s. Nat Commun. 2024 Nov 12;15(1):9801. doi: 10.1038/s41467-024-52528-7. Nat Commun. 2024. PMID: 39532835 Free PMC article. Clinical Trial.
Immune-related events in individuals with solid tumors on immunotherapy associate with Th17 and Th2 signatures.
Kao CJ, Charmsaz S, Alden SL, Brancati M, Li HL, Balaji A, Munjal K, Howe K, Mitchell S, Leatherman J, Griffin E, Nakazawa M, Tsai HL, Danilova L, Thoburn C, Gizzi J, Gross NE, Hernandez A, Coyne EM, Shin SM, Babu JS, Apostol GW, Durham J, Christmas BJ, Konig MF, Lipson EJ, Naidoo J, Cappelli LC, Pabani A, Ged Y, Baretti M, Brahmer J, Hoffman-Censits J, Seiwert TY, Garonce-Hediger R, Guha A, Bansal S, Tang L, Jaffee EM, Chandler GS, Mohindra R, Ho WJ, Yarchoan M. Kao CJ, et al. Among authors: charmsaz s. J Clin Invest. 2024 Aug 29;134(20):e176567. doi: 10.1172/JCI176567. J Clin Invest. 2024. PMID: 39403935 Free PMC article. Clinical Trial.
Phosphodiesterase-5 inhibition collaborates with vaccine-based immunotherapy to reprogram myeloid cells in pancreatic ductal adenocarcinoma.
Gross NE, Zhang Z, Mitchell JT, Charmsaz S, Hernandez AG, Coyne EM, Shin SM, Vargas Carvajal DC, Sidiropoulos DN, Cho Y, Mo G, Yuan X, Cannon C, Suresh Babu J, Lyman MR, Armstrong T, Kagohara LT, Bever KM, Le DT, Jaffee EM, Fertig EJ, Ho WJ. Gross NE, et al. Among authors: charmsaz s. JCI Insight. 2024 Aug 6;9(18):e179292. doi: 10.1172/jci.insight.179292. JCI Insight. 2024. PMID: 39106104 Free PMC article.
Fibroblasts in the Aged Pancreas Drive Pancreatic Cancer Progression.
Zabransky DJ, Chhabra Y, Fane ME, Kartalia E, Leatherman JM, Hüser L, Zimmerman JW, Delitto D, Han S, Armstrong TD, Charmsaz S, Guinn S, Pramod S, Thompson ED, Hughes SJ, O'Connell J, Egan JM, Jaffee EM, Weeraratna AT. Zabransky DJ, et al. Among authors: charmsaz s. Cancer Res. 2024 Apr 15;84(8):1221-1236. doi: 10.1158/0008-5472.CAN-24-0086. Cancer Res. 2024. PMID: 38330147
Multimodal immune phenotyping reveals microbial-T cell interactions that shape pancreatic cancer.
Li Y, Chang RB, Stone ML, Delman D, Markowitz K, Xue Y, Coho H, Herrera VM, Li JH, Zhang L, Choi-Bose S, Giannone M, Shin SM, Coyne EM, Hernandez A, Gross NE, Charmsaz S, Ho WJ, Lee JW, Beatty GL. Li Y, et al. Among authors: charmsaz s. Cell Rep Med. 2024 Feb 20;5(2):101397. doi: 10.1016/j.xcrm.2024.101397. Epub 2024 Feb 1. Cell Rep Med. 2024. PMID: 38307029 Free PMC article.
CTC-5: A novel digital pathology approach to characterise circulating tumour cell biodiversity.
Ffrench B, Kashdan E, Huang Y, Spillane CD, Cocchiglia S, Charmsaz S, Varešlija D, O'Brien C, Scholz D, Martin C, Gallagher M, Brooks DA, Brooks RD, Selemidis S, Gleeson N, AbuSaadeh F, O'Riain C, Kamran W, Flavin R, Young L, O'Toole SA, O'Leary JJ. Ffrench B, et al. Among authors: charmsaz s. Heliyon. 2023 Jan 18;9(1):e13044. doi: 10.1016/j.heliyon.2023.e13044. eCollection 2023 Jan. Heliyon. 2023. PMID: 36747925 Free PMC article.
Dynamic epi-transcriptomic landscape mapping with disease progression in estrogen receptor-positive breast cancer.
Keelan S, Ola M, Charmsaz S, Cocchiglia S, Ottaviani D, Hickey S, Purcell S, Bane F, Hegarty A, Doherty B, Sheehan K, Hudson L, Cosgrove N, Roux B, Laine M, Greene G, Varešlija D, Hill AK, Young L. Keelan S, et al. Among authors: charmsaz s. Cancer Commun (Lond). 2023 May;43(5):615-619. doi: 10.1002/cac2.12407. Epub 2023 Jan 20. Cancer Commun (Lond). 2023. PMID: 36670046 Free PMC article. No abstract available.
CyTOF protocol for immune monitoring of solid tumors from mouse models.
Shin SM, Hernandez A, Coyne E, Munjal K, Gross NE, Charmsaz S, Yuan X, Yang H, Ho WJ. Shin SM, et al. Among authors: charmsaz s. STAR Protoc. 2023 Mar 17;4(1):101949. doi: 10.1016/j.xpro.2022.101949. Epub 2022 Dec 19. STAR Protoc. 2023. PMID: 36538397 Free PMC article.
34 results