Basson A - Search Results

1

Building Metabolically Stable and Potent Anti-HIV Thioether-Lipid Analogues of Tenofovir Exalidex: A thorough Pharmacological Analysis.

D'Erasmo MP, Sharma SK, Pribut N, Basson A, Dasari M, Bartsch P, Iskandar SE, Giesler KE, Burton S, Derdeyn CA, Liotta DC, Miller EJ. D'Erasmo MP, et al. Among authors: basson a. J Med Chem. 2024 Oct 24;67(20):18204-18220. doi: 10.1021/acs.jmedchem.4c01510. Epub 2024 Oct 16. J Med Chem. 2024. PMID: 39411803 Free PMC article.

2

Aryl Substituted Benzimidazolones as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors.

Pribut N, Basson AE, van Otterlo WAL, Liotta DC, Pelly SC. Pribut N, et al. Among authors: basson ae. ACS Med Chem Lett. 2019 Jan 17;10(2):196-202. doi: 10.1021/acsmedchemlett.8b00549. eCollection 2019 Feb 14. ACS Med Chem Lett. 2019. PMID: 30783503 Free PMC article.

3

ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties.

Pribut N, D'Erasmo M, Dasari M, Giesler KE, Iskandar S, Sharma SK, Bartsch PW, Raghuram A, Bushnev A, Hwang SS, Burton SL, Derdeyn CA, Basson AE, Liotta DC, Miller EJ. Pribut N, et al. Among authors: basson ae. J Med Chem. 2021 Sep 9;64(17):12917-12937. doi: 10.1021/acs.jmedchem.1c01083. Epub 2021 Aug 30. J Med Chem. 2021. PMID: 34459598

4

Expanding the toolbox of metabolically stable lipid prodrug strategies.

Toti KS, Pribut N, D'Erasmo M, Dasari M, Sharma SK, Bartsch PW, Burton SL, Gold HB, Bushnev A, Derdeyn CA, Basson AE, Liotta DC, Miller EJ. Toti KS, et al. Among authors: basson ae. Front Pharmacol. 2023 Jan 6;13:1083284. doi: 10.3389/fphar.2022.1083284. eCollection 2022. Front Pharmacol. 2023. PMID: 36686712 Free PMC article.

5

Novel Cyclopropyl-Indole Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors.

Hassam M, Basson AE, Liotta DC, Morris L, van Otterlo WA, Pelly SC. Hassam M, et al. Among authors: basson ae. ACS Med Chem Lett. 2012 May 2;3(6):470-5. doi: 10.1021/ml3000462. eCollection 2012 Jun 14. ACS Med Chem Lett. 2012. PMID: 24900496 Free PMC article.

6

Novel indole sulfides as potent HIV-1 NNRTIs.

Brigg S, Pribut N, Basson AE, Avgenikos M, Venter R, Blackie MA, van Otterlo WAL, Pelly SC. Brigg S, et al. Among authors: basson ae. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1580-1584. doi: 10.1016/j.bmcl.2016.02.006. Epub 2016 Feb 4. Bioorg Med Chem Lett. 2016. PMID: 26876929

7

Application of the Huisgen cycloaddition and 'click' reaction toward various 1,2,3-triazoles as HIV non-nucleoside reverse transcriptase inhibitors.

Pribut N, Veale CG, Basson AE, van Otterlo WA, Pelly SC. Pribut N, et al. Among authors: basson ae. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3700-4. doi: 10.1016/j.bmcl.2016.05.082. Epub 2016 May 28. Bioorg Med Chem Lett. 2016. PMID: 27287366

8

Novel indole based NNRTIs with improved potency against wild type and resistant HIV.

Müller R, Mulani I, Basson AE, Pribut N, Hassam M, Morris L, van Otterlo WAL, Pelly SC. Müller R, et al. Among authors: basson ae. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4376-4380. doi: 10.1016/j.bmcl.2014.08.020. Epub 2014 Aug 13. Bioorg Med Chem Lett. 2014. PMID: 25176191

9

K103N, V106M and Y188L Significantly Reduce HIV-1 Subtype C Phenotypic Susceptibility to Doravirine.

Reddy N, Papathanasopoulos M, Steegen K, Basson AE. Reddy N, et al. Among authors: basson ae. Viruses. 2024 Sep 20;16(9):1493. doi: 10.3390/v16091493. Viruses. 2024. PMID: 39339969 Free PMC article.

10

HIV-1 re-suppression on a first-line regimen despite the presence of phenotypic drug resistance.

Basson AE, Charalambous S, Hoffmann CJ, Morris L. Basson AE, et al. PLoS One. 2020 Jun 18;15(6):e0234937. doi: 10.1371/journal.pone.0234937. eCollection 2020. PLoS One. 2020. PMID: 32555643 Free PMC article.

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