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Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target.
Zhang H, Thai PN, Shivnaraine RV, Ren L, Wu X, Siepe DH, Liu Y, Tu C, Shin HS, Caudal A, Mukherjee S, Leitz J, Wen WTL, Liu W, Zhu W, Chiamvimonvat N, Wu JC. Zhang H, et al. Among authors: ren l. Cell. 2024 Oct 12:S0092-8674(24)01092-4. doi: 10.1016/j.cell.2024.09.034. Online ahead of print. Cell. 2024. PMID: 39413786
Prestin amplifies cardiac motor functions.
Zhang XD, Thai PN, Ren L, Perez Flores MC, Ledford HA, Park S, Lee JH, Sihn CR, Chang CW, Chen WC, Timofeyev V, Zuo J, Chan JW, Yamoah EN, Chiamvimonvat N. Zhang XD, et al. Among authors: ren l. Cell Rep. 2021 May 4;35(5):109097. doi: 10.1016/j.celrep.2021.109097. Cell Rep. 2021. PMID: 33951436 Free PMC article.
Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac stem cell-based therapy.
Sirish P, Thai PN, Lee JH, Yang J, Zhang XD, Ren L, Li N, Timofeyev V, Lee KSS, Nader CE, Rowland DJ, Yechikov S, Ganaga S, Young N, Lieu DK, Yamoah EN, Hammock BD, Chiamvimonvat N. Sirish P, et al. Among authors: ren l. Stem Cells Transl Med. 2020 Dec;9(12):1570-1584. doi: 10.1002/sctm.20-0143. Epub 2020 Aug 13. Stem Cells Transl Med. 2020. PMID: 32790136 Free PMC article.
Disruption of protein quality control of the human ether-à-go-go related gene K+ channel results in profound long QT syndrome.
Ledford HA, Ren L, Thai PN, Park S, Timofeyev V, Sirish P, Xu W, Emigh AM, Priest JR, Perez MV, Ashley EA, Yarov-Yarovoy V, Yamoah EN, Zhang XD, Chiamvimonvat N. Ledford HA, et al. Among authors: ren l. Heart Rhythm. 2022 Feb;19(2):281-292. doi: 10.1016/j.hrthm.2021.10.005. Epub 2021 Oct 9. Heart Rhythm. 2022. PMID: 34634443 Free PMC article.
Disruption of mitochondria-sarcoplasmic reticulum microdomain connectomics contributes to sinus node dysfunction in heart failure.
Ren L, Gopireddy RR, Perkins G, Zhang H, Timofeyev V, Lyu Y, Diloretto DA, Trinh P, Sirish P, Overton JL, Xu W, Grainger N, Xiang YK, Dedkova EN, Zhang XD, Yamoah EN, Navedo MF, Thai PN, Chiamvimonvat N. Ren L, et al. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2206708119. doi: 10.1073/pnas.2206708119. Epub 2022 Aug 31. Proc Natl Acad Sci U S A. 2022. PMID: 36044551 Free PMC article.
Atomistic mechanisms of the regulation of small-conductance Ca2+-activated K+ channel (SK2) by PIP2.
Woltz RL, Zheng Y, Choi W, Ngo K, Trinh P, Ren L, Thai PN, Harris BJ, Han Y, Rouen KC, Mateos DL, Jian Z, Chen-Izu Y, Dickson EJ, Yamoah EN, Yarov-Yarovoy V, Vorobyov I, Zhang XD, Chiamvimonvat N. Woltz RL, et al. Among authors: ren l. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2318900121. doi: 10.1073/pnas.2318900121. Epub 2024 Sep 17. Proc Natl Acad Sci U S A. 2024. PMID: 39288178 Free PMC article.
7,112 results