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Page 1
Targetable treatment resistance in thyroid cancer with clonal hematopoiesis.
Tiedje V, Vela PS, Yang JL, Untch BR, Boucai L, Stonestrom AJ, Costa AB, Expósito SF, Srivastava A, Kerpelev M, Greenberg J, Wereski M, Kulick A, Chen K, Qin T, Im SY, Krishnan A, Martinez Benitez AR, Pluvinet R, Sahin M, Menghrajani K, Krishnamoorthy GP, de Stanchina E, Zehir A, Satija R, Knauf J, Bowman RL, Esteller M, Devlin S, Berger MF, Koche RP, Fagin JA, Levine RL. Tiedje V, et al. Among authors: berger mf. bioRxiv [Preprint]. 2024 Oct 11:2024.10.10.617685. doi: 10.1101/2024.10.10.617685. bioRxiv. 2024. PMID: 39415999 Free PMC article. Preprint.
Tracking clonal evolution of drug resistance in ovarian cancer patients by exploiting structural variants in cfDNA.
Williams MJ, Vázquez-García I, Tam G, Wu M, Varice N, Havasov E, Shi H, Satas G, Lees HJ, Lee JJ, Myers MA, Zatzman M, Rusk N, Ali E, Shah RH, Berger MF, Mohibullah N, Lakhman Y, Chi DS, Abu-Rustum NR, Aghajanian C, McPherson A, Zamarin D, Loomis B, Weigelt B, Friedman CF, Shah SP. Williams MJ, et al. Among authors: berger mf. bioRxiv [Preprint]. 2024 Aug 23:2024.08.21.609031. doi: 10.1101/2024.08.21.609031. bioRxiv. 2024. PMID: 39229105 Free PMC article. Preprint.
Tumor suppressor heterozygosity and homologous recombination deficiency mediate resistance to front-line therapy in breast cancer.
Safonov A, Marra A, Bandlamudi C, O'Leary B, Wubbenhorst B, Ferraro E, Moiso E, Lee M, An J, Donoghue MTA, Will M, Pareja F, Nizialek E, Lukashchuk N, Sofianopoulou E, Liu Y, Huang X, Ahmed M, Mehine MM, Ross D, Mandelker D, Ladanyi M, Schultz N, Berger MF, Scaltriti M, Reis-Filho JS, Li BT, Offit K, Norton L, Shen R, Shah S, Maxwell KN, Couch F, Domchek SM, Solit DB, Nathanson KL, Robson ME, Turner NC, Chandarlapaty S, Razavi P. Safonov A, et al. Among authors: berger mf. bioRxiv [Preprint]. 2024 Aug 26:2024.02.05.578934. doi: 10.1101/2024.02.05.578934. bioRxiv. 2024. PMID: 39253462 Free PMC article. Preprint.
Clinicogenomic landscape of pancreatic adenocarcinoma identifies KRAS mutant dosage as prognostic of overall survival.
Varghese AM, Perry MA, Chou JF, Nandakumar S, Muldoon D, Erakky A, Zucker A, Fong C, Mehine M, Nguyen B, Basturk O, Balogun F, Kelsen DP, Brannon AR, Mandelker D, Vakiani E, Park W, Yu KH, Stadler ZK, Schattner MA, Jarnagin WR, Wei AC, Chakravarty D, Capanu M, Schultz N, Berger MF, Iacobuzio-Donahue CA, Bandlamudi C, O'Reilly EM. Varghese AM, et al. Among authors: berger mf. Nat Med. 2025 Jan 3. doi: 10.1038/s41591-024-03362-3. Online ahead of print. Nat Med. 2025. PMID: 39753968
A deep multiple instance learning framework improves microsatellite instability detection from tumor next generation sequencing.
Ziegler J, Hechtman JF, Rana S, Ptashkin RN, Jayakumaran G, Middha S, Chavan SS, Vanderbilt C, DeLair D, Casanova J, Shia J, DeGroat N, Benayed R, Ladanyi M, Berger MF, Fuchs TJ, Brannon AR, Zehir A. Ziegler J, et al. Among authors: berger mf. Nat Commun. 2025 Jan 2;16(1):136. doi: 10.1038/s41467-024-54970-z. Nat Commun. 2025. PMID: 39746944 Free PMC article.
Pan-cancer analysis of biallelic inactivation in tumor suppressor genes identifies KEAP1 zygosity as a predictive biomarker in lung cancer.
Zucker M, Perry MA, Gould SI, Elkrief A, Safonov A, Thummalapalli R, Mehine M, Chakravarty D, Brannon AR, Ladanyi M, Razavi P, Donoghue MTA, Murciano-Goroff YR, Grigoriadis K, McGranahan N, Jamal-Hanjani M, Swanton C, Chen Y, Shen R, Chandarlapaty S, Solit DB, Schultz N, Berger MF, Chang J, Schoenfeld AJ, Sánchez-Rivera FJ, Reznik E, Bandlamudi C. Zucker M, et al. Among authors: berger mf. Cell. 2024 Dec 12:S0092-8674(24)01327-8. doi: 10.1016/j.cell.2024.11.010. Online ahead of print. Cell. 2024. PMID: 39701102 Free article.
Non-RB1 germline cancer predisposing variants found in retinoblastoma patients.
Rodriguez Barreto AM, Walsh MF, Robbins MA, Mauguen A, Fiala EM, Olcese C, Haggag-Lindgren D, Mandelker D, Francis JH, Berger MF, Friedman DN, Offit K, Abramson DH. Rodriguez Barreto AM, et al. Among authors: berger mf. Genet Med Open. 2024 Mar 6;2:101836. doi: 10.1016/j.gimo.2024.101836. eCollection 2024. Genet Med Open. 2024. PMID: 39669595 Free PMC article.
Differences in Ancestry and Presence of Gastric Precursor Lesions in Individuals With Young- and Average-Onset Gastric Cancer.
Magahis PT, Cornet N, Tang L, Arora K, Hingorani N, King S, Markowitz AJ, Schattner M, Shimada S, Maron SB, Vardhana S, Lumish M, Cercek A, Janjigian YY, Coit D, Mendelsohn RB, Berger MF, Strong VE, Stadler ZK, Laszkowska M. Magahis PT, et al. Among authors: berger mf. Cancer Med. 2024 Dec;13(23):e70451. doi: 10.1002/cam4.70451. Cancer Med. 2024. PMID: 39629931 Free PMC article.
394 results