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A STAT3 Degrader Demonstrates Pre-clinical Efficacy in Venetoclax resistant Acute Myeloid Leukemia.
Chakraborty S, Morganti C, Pena BR, Zhang H, Verma D, Zaldana K, Gitego N, Ma F, Aluri S, Pradhan K, Gordon S, Mantzaris I, Goldfinger M, Feldman E, Gritsman K, Shi Y, Hubner S, Qiu YH, Brown BD, Skwarska A, Verma A, Konopleva M, Tabe Y, Gavathiotis E, Colla S, Gollob J, Dey J, Kornblau SM, Koralov SB, Ito K, Shastri A. Chakraborty S, et al. Among authors: gavathiotis e. bioRxiv [Preprint]. 2024 Aug 7:2024.08.05.599788. doi: 10.1101/2024.08.05.599788. bioRxiv. 2024. PMID: 39211137 Free PMC article. Preprint.
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MY, Zhu D, Yu F, Xu J, Yarahmady A, Chen H, Huang Y, Amin S, Zacharioudakis E, Chen X, Holtzman DM, Mok SA, Gavathiotis E, Sinha SC, Cheng F, Luo W, Gong S, Gan L. Carling GK, et al. Among authors: gavathiotis e. bioRxiv [Preprint]. 2024 Jan 25:2024.01.24.577107. doi: 10.1101/2024.01.24.577107. bioRxiv. 2024. Update in: Neuron. 2024 Dec 4;112(23):3877-3896.e8. doi: 10.1016/j.neuron.2024.09.006 PMID: 38328219 Free PMC article. Updated. Preprint.
Reconstitution of Rab11-FIP4 Expression Rescues Cellular Homeostasis in Cystinosis.
Rahman F, Johnson JL, Ait Kbaich M, Meneses-Salas E, Shukla A, Chen D, Kiosses WB, Gavathiotis E, Cuervo AM, Cherqui S, Catz SD. Rahman F, et al. Among authors: gavathiotis e. Mol Cell Biol. 2024;44(12):577-589. doi: 10.1080/10985549.2024.2410814. Epub 2024 Oct 22. Mol Cell Biol. 2024. PMID: 39434668 Free PMC article.
Comprehensive functional evaluation of head and neck squamous cell carcinoma with BH3-profiling demonstrates apoptotic competency and therapeutic efficacy of BH3-mimetics.
Li D, Lopez A, Shrivastava N, Chan W, Thomas C, Burk R, Segall J, Augustine S, Rosenblatt G, Mehta V, Schiff BA, Smith RV, Prystowsky MB, Schlecht NF, Guha C, Gavathiotis E, Ow TJ. Li D, et al. Among authors: gavathiotis e. Oral Oncol. 2024 Dec;159:107069. doi: 10.1016/j.oraloncology.2024.107069. Epub 2024 Oct 17. Oral Oncol. 2024. PMID: 39423550
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Carling GK, Fan L, Foxe NR, Norman K, Wong MY, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A, Ye P, Chen H, Huang Y, Amin S, Sereda R, Lopez-Lee C, Zacharioudakis E, Chen X, Xu J, Cheng F, Gavathiotis E, Cuervo AM, Holtzman DM, Mok SA, Sinha SC, Sidoli S, Ratan RR, Luo W, Gong S, Gan L. Carling GK, et al. Among authors: gavathiotis e. Neuron. 2024 Dec 4;112(23):3877-3896.e8. doi: 10.1016/j.neuron.2024.09.006. Epub 2024 Sep 30. Neuron. 2024. PMID: 39353433 Free article.
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