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Page 1
Structural requirements for the specific binding of CRABP2 to cyclin D3.
Pastok MW, Tomlinson CWE, Turberville S, Butler AM, Baslé A, Noble MEM, Endicott JA, Pohl E, Tatum NJ. Pastok MW, et al. Among authors: noble mem. Structure. 2024 Dec 5;32(12):2301-2315.e6. doi: 10.1016/j.str.2024.09.020. Epub 2024 Oct 16. Structure. 2024. PMID: 39419021 Free article.
Fragment expansion with NUDELs - poised DNA-encoded libraries.
Salvini CLA, Darlot B, Davison J, Martin MP, Tudhope SJ, Turberville S, Kawamura A, Noble MEM, Wedge SR, Crawford JJ, Waring MJ. Salvini CLA, et al. Among authors: noble mem. Chem Sci. 2023 Jul 12;14(31):8288-8294. doi: 10.1039/d3sc01171b. eCollection 2023 Aug 9. Chem Sci. 2023. PMID: 37564419 Free PMC article.
Structural requirements for the specific binding of CRABP2 to cyclin D3.
Pastok MW, Tomlinson CWE, Turberville S, Butler AM, Baslé A, Noble MEM, Endicott JA, Pohl E, Tatum NJ. Pastok MW, et al. Among authors: noble mem. Structure. 2024 Dec 5;32(12):2450. doi: 10.1016/j.str.2024.10.027. Epub 2024 Oct 26. Structure. 2024. PMID: 39489909 Free article. No abstract available.
Targeting Cytotoxic Agents through EGFR-Mediated Covalent Binding and Release.
Morese PA, Anthony N, Bodnarchuk M, Jennings C, Martin MP, Noble RA, Phillips N, Thomas HD, Wang LZ, Lister A, Noble MEM, Ward RA, Wedge SR, Stewart HL, Waring MJ. Morese PA, et al. Among authors: noble mem. J Med Chem. 2023 Sep 14;66(17):12324-12341. doi: 10.1021/acs.jmedchem.3c00845. Epub 2023 Aug 30. J Med Chem. 2023. PMID: 37647129 Free PMC article.
Cryo-EM structure of the CDK2-cyclin A-CDC25A complex.
Rowland RJ, Korolchuk S, Salamina M, Tatum NJ, Ault JR, Hart S, Turkenburg JP, Blaza JN, Noble MEM, Endicott JA. Rowland RJ, et al. Among authors: noble mem. Nat Commun. 2024 Aug 9;15(1):6807. doi: 10.1038/s41467-024-51135-w. Nat Commun. 2024. PMID: 39122719 Free PMC article.
The CCP4 suite: integrative software for macromolecular crystallography.
Agirre J, Atanasova M, Bagdonas H, Ballard CB, Baslé A, Beilsten-Edmands J, Borges RJ, Brown DG, Burgos-Mármol JJ, Berrisford JM, Bond PS, Caballero I, Catapano L, Chojnowski G, Cook AG, Cowtan KD, Croll TI, Debreczeni JÉ, Devenish NE, Dodson EJ, Drevon TR, Emsley P, Evans G, Evans PR, Fando M, Foadi J, Fuentes-Montero L, Garman EF, Gerstel M, Gildea RJ, Hatti K, Hekkelman ML, Heuser P, Hoh SW, Hough MA, Jenkins HT, Jiménez E, Joosten RP, Keegan RM, Keep N, Krissinel EB, Kolenko P, Kovalevskiy O, Lamzin VS, Lawson DM, Lebedev AA, Leslie AGW, Lohkamp B, Long F, Malý M, McCoy AJ, McNicholas SJ, Medina A, Millán C, Murray JW, Murshudov GN, Nicholls RA, Noble MEM, Oeffner R, Pannu NS, Parkhurst JM, Pearce N, Pereira J, Perrakis A, Powell HR, Read RJ, Rigden DJ, Rochira W, Sammito M, Sánchez Rodríguez F, Sheldrick GM, Shelley KL, Simkovic F, Simpkin AJ, Skubak P, Sobolev E, Steiner RA, Stevenson K, Tews I, Thomas JMH, Thorn A, Valls JT, Uski V, Usón I, Vagin A, Velankar S, Vollmar M, Walden H, Waterman D, Wilson KS, Winn MD, Winter G, Wojdyr M, Yamashita K. Agirre J, et al. Among authors: noble mem. Acta Crystallogr D Struct Biol. 2023 Jun 1;79(Pt 6):449-461. doi: 10.1107/S2059798323003595. Epub 2023 May 30. Acta Crystallogr D Struct Biol. 2023. PMID: 37259835 Free PMC article.
Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.
Davison G, Martin MP, Turberville S, Dormen S, Heath R, Heptinstall AB, Lawson M, Miller DC, Ng YM, Sanderson JN, Hope I, Wood DJ, Cano C, Endicott JA, Hardcastle IR, Noble MEM, Waring MJ. Davison G, et al. Among authors: noble mem. J Med Chem. 2022 Nov 24;65(22):15416-15432. doi: 10.1021/acs.jmedchem.2c01357. Epub 2022 Nov 11. J Med Chem. 2022. PMID: 36367089 Free PMC article.
78 results