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Page 1
Small molecule modulation of insulin receptor-insulin like growth factor-1 receptor heterodimers in human endothelial cells.
Myers CG, Viswambharan H, Haywood NJ, Bridge K, Turvey S, Armstrong T, Lunn L, Meakin PJ, Porter KE, Clavane EM, Beech DJ, Cubbon RM, Wheatcroft SB, McPhillie MJ, Issad T, Fishwick CW, Kearney MT, Simmons KJ. Myers CG, et al. Among authors: meakin pj. Mol Cell Endocrinol. 2024 Dec 1;594:112387. doi: 10.1016/j.mce.2024.112387. Epub 2024 Oct 16. Mol Cell Endocrinol. 2024. PMID: 39419341 Free article.
The diabetic myocardial transcriptome reveals Erbb3 and Hspa2 as a novel biomarkers of incident heart failure.
Conning-Rowland MS, Giannoudi M, Drozd M, Brown OI, Yuldasheva NY, Cheng CW, Meakin PJ, Straw S, Gierula J, Ajjan RA, Kearney MT, Levelt E, Roberts LD, Griffin KJ, Cubbon RM. Conning-Rowland MS, et al. Among authors: meakin pj. Cardiovasc Res. 2024 Dec 4;120(15):1898-1906. doi: 10.1093/cvr/cvae181. Cardiovasc Res. 2024. PMID: 39180332 Free PMC article.
DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks.
Pinto LM, Pailas A, Bondarchenko M, Sharma AB, Neumann K, Rizzo AJ, Jeanty C, Nicot N, Racca C, Graham MK, Naughton C, Liu Y, Chen CL, Meakin PJ, Gilbert N, Britton S, Meeker AK, Heaphy CM, Larminat F, Van Dyck E. Pinto LM, et al. Among authors: meakin pj. Nucleic Acids Res. 2024 Feb 9;52(3):1136-1155. doi: 10.1093/nar/gkad1141. Nucleic Acids Res. 2024. PMID: 38038252 Free PMC article.
The β-Secretase BACE1 Drives Fibroblast Activation in Systemic Sclerosis through the APP/β-Catenin/Notch Signaling Axis.
Wasson CW, De Lorenzis E, Clavane EM, Ross RL, Walker KA, Caballero-Ruiz B, Antinozzi C, Wells R, Migneco G, Brown JMY, Turvey SJ, Simmons KJ, Riobo-Del Galdo NA, Di Luigi L, McKimmie CS, Del Galdo F, Meakin PJ. Wasson CW, et al. Among authors: meakin pj. J Invest Dermatol. 2024 Oct;144(10):2197-2210.e4. doi: 10.1016/j.jid.2024.03.024. Epub 2024 Apr 1. J Invest Dermatol. 2024. PMID: 38570030 Free article.
BACE1: More than just a β-secretase.
Taylor HA, Przemylska L, Clavane EM, Meakin PJ. Taylor HA, et al. Among authors: meakin pj. Obes Rev. 2022 Jul;23(7):e13430. doi: 10.1111/obr.13430. Epub 2022 Feb 4. Obes Rev. 2022. PMID: 35119166 Free PMC article. Review.
Endothelial Cell Fibrin Gel Angiogenesis Bead Assay.
Clavane EM, Taylor HA, Cubbon RM, Meakin PJ. Clavane EM, et al. Among authors: meakin pj. Methods Mol Biol. 2022;2441:321-327. doi: 10.1007/978-1-0716-2059-5_25. Methods Mol Biol. 2022. PMID: 35099748
Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction.
Meakin PJ, Coull BM, Tuharska Z, McCaffery C, Akoumianakis I, Antoniades C, Brown J, Griffin KJ, Platt F, Ozber CH, Yuldasheva NY, Makava N, Skromna A, Prescott A, McNeilly AD, Siddiqui M, Palmer CN, Khan F, Ashford ML. Meakin PJ, et al. J Clin Invest. 2020 Aug 3;130(8):4104-4117. doi: 10.1172/JCI122237. J Clin Invest. 2020. PMID: 32407295 Free PMC article.
Corrigendum to "The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling" [Metab Clin Exp 85 (2018) 59-75].
Botteri G, Salvadó L, Gumà A, Hamilton DL, Meakin PJ, Montagut G, Ashford MLJ, Ceperuelo-Mallafré V, Fernández-Veledo S, Vendrell J, Calderón-Dominguez M, Serra D, Herrero L, Pizarro J, Barroso E, Palomer X, Vázquez-Carrera M. Botteri G, et al. Among authors: meakin pj. Metabolism. 2019 Jul;96:101-102. doi: 10.1016/j.metabol.2019.04.009. Epub 2019 Apr 18. Metabolism. 2019. PMID: 31005247 No abstract available.
30 results