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Page 1
Early evolutionary branching across spatial domains predisposes to clonal replacement under chemotherapy in neuroblastoma.
Karlsson J, Yasui H, Mañas A, Andersson N, Hansson K, Aaltonen K, Jansson C, Durand G, Ravi N, Ferro M, Yang M, Chattopadhyay S, Paulsson K, Spierings D, Foijer F, Valind A, Bexell D, Gisselsson D. Karlsson J, et al. Among authors: bexell d. Nat Commun. 2024 Oct 18;15(1):8992. doi: 10.1038/s41467-024-53334-x. Nat Commun. 2024. PMID: 39419962 Free PMC article.
Breast cancer associated CD169+ macrophages possess broad immunosuppressive functions but enhance antibody secretion by activated B cells.
Gunnarsdottir FB, Briem O, Lindgren AY, Källberg E, Andersen C, Grenthe R, Rosenqvist C, Millrud CR, Wallgren M, Viklund H, Bexell D, Johansson ME, Hedenfalk I, Hagerling C, Leandersson K. Gunnarsdottir FB, et al. Among authors: bexell d. Front Immunol. 2023 Jun 19;14:1180209. doi: 10.3389/fimmu.2023.1180209. eCollection 2023. Front Immunol. 2023. PMID: 37404831 Free PMC article.
Macrophage infiltration promotes regrowth in MYCN-amplified neuroblastoma after chemotherapy.
Valind A, Verhoeven BM, Enoksson J, Karlsson J, Christensson G, Mañas A, Aaltonen K, Jansson C, Bexell D, Baryawno N, Gisselsson D, Hagerling C. Valind A, et al. Among authors: bexell d. Oncoimmunology. 2023 Mar 1;12(1):2184130. doi: 10.1080/2162402X.2023.2184130. eCollection 2023. Oncoimmunology. 2023. PMID: 36875552 Free PMC article.
Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance.
Mañas A, Aaltonen K, Andersson N, Hansson K, Adamska A, Seger A, Yasui H, van den Bos H, Radke K, Esfandyari J, Bhave MS, Karlsson J, Spierings D, Foijer F, Gisselsson D, Bexell D. Mañas A, et al. Among authors: bexell d. Sci Adv. 2022 Oct 28;8(43):eabq4617. doi: 10.1126/sciadv.abq4617. Epub 2022 Oct 28. Sci Adv. 2022. PMID: 36306349 Free PMC article.
Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis.
Grigoryan A, Zacharaki D, Balhuizen A, Côme CR, Garcia AG, Hidalgo Gil D, Frank AK, Aaltonen K, Mañas A, Esfandyari J, Kjellman P, Englund E, Rodriguez C, Sime W, Massoumi R, Kalantari N, Prithiviraj S, Li Y, Dupard SJ, Isaksson H, Madsen CD, Porse BT, Bexell D, Bourgine PE. Grigoryan A, et al. Among authors: bexell d. Sci Transl Med. 2022 Oct 12;14(666):eabm6391. doi: 10.1126/scitranslmed.abm6391. Epub 2022 Oct 12. Sci Transl Med. 2022. PMID: 36223446
Anti-tumor effects of rigosertib in high-risk neuroblastoma.
Radke K, Hansson K, Sjölund J, Wolska M, Karlsson J, Esfandyari J, Pietras K, Aaltonen K, Gisselsson D, Bexell D. Radke K, et al. Among authors: bexell d. Transl Oncol. 2021 Aug;14(8):101149. doi: 10.1016/j.tranon.2021.101149. Epub 2021 Jun 9. Transl Oncol. 2021. PMID: 34118691 Free PMC article.
Inhibition of fatty acid synthesis induces differentiation and reduces tumor burden in childhood neuroblastoma.
Ruiz-Pérez MV, Sainero-Alcolado L, Oliynyk G, Matuschek I, Balboni N, Ubhayasekera SJKA, Snaebjornsson MT, Makowski K, Aaltonen K, Bexell D, Serra D, Nilsson R, Bergquist J, Schulze A, Arsenian-Henriksson M. Ruiz-Pérez MV, et al. Among authors: bexell d. iScience. 2021 Feb 1;24(2):102128. doi: 10.1016/j.isci.2021.102128. eCollection 2021 Feb 19. iScience. 2021. PMID: 33659885 Free PMC article.
Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma.
Hansson K, Radke K, Aaltonen K, Saarela J, Mañas A, Sjölund J, Smith EM, Pietras K, Påhlman S, Wennerberg K, Gisselsson D, Bexell D. Hansson K, et al. Among authors: bexell d. Sci Transl Med. 2020 Sep 23;12(562):eaba4434. doi: 10.1126/scitranslmed.aba4434. Sci Transl Med. 2020. PMID: 32967973
44 results