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Supporting Surgeon-Scientists to Prosper as Researchers.
Harman JEB, Linehan DC, Naganathan A. Harman JEB, et al. Among authors: linehan dc. JAMA Surg. 2024 Oct 2. doi: 10.1001/jamasurg.2024.2749. Online ahead of print. JAMA Surg. 2024. PMID: 39356503
Pan-lysyl oxidase inhibition disrupts fibroinflammatory tumor stroma, rendering cholangiocarcinoma susceptible to chemotherapy.
Burchard PR, Ruffolo LI, Ullman NA, Dale BS, Dave YA, Hilty BK, Ye J, Georger M, Jewell R, Miller C, De Las Casas L, Jarolimek W, Perryman L, Byrne MM, Loria A, Marin C, Chávez Villa M, Yeh JJ, Belt BA, Linehan DC, Hernandez-Alejandro R. Burchard PR, et al. Among authors: linehan dc. Hepatol Commun. 2024 Aug 5;8(8):e0502. doi: 10.1097/HC9.0000000000000502. eCollection 2024 Aug 1. Hepatol Commun. 2024. PMID: 39101793 Free PMC article.
Determination of permissive and restraining cancer-associated fibroblast (DeCAF) subtypes.
Peng XL, Kharitonova EV, Xu Y, Kearney JF, Luan C, Chan PS, Hariharan A, McCabe IC, Leary JR, Morrison AB, Trembath HE, LaBella ME, Herera Loeza SG, Cliff A, Kim HJ, Belt BA, Panni RZ, Linehan DC, Damrauer JS, Iuga AC, Kim WY, Rashid NU, Yeh JJ. Peng XL, et al. Among authors: linehan dc. bioRxiv [Preprint]. 2024 May 17:2024.05.14.594197. doi: 10.1101/2024.05.14.594197. bioRxiv. 2024. PMID: 38798565 Free PMC article. Preprint.
Smad4 restricts injury-provoked biliary proliferation and carcinogenesis.
Alexander WB, Wang W, Hill MA, O'Dell MR, Ruffolo LI, Guo B, Jackson KM, Ullman N, Friedland SC, McCall MN, Patel A, Figueroa-Guilliani N, Georger M, Belt BA, Whitney-Miller CL, Linehan DC, Murphy PJ, Hezel AF. Alexander WB, et al. Among authors: linehan dc. Dis Model Mech. 2024 Jun 1;17(6):dmm050358. doi: 10.1242/dmm.050358. Epub 2024 Feb 28. Dis Model Mech. 2024. PMID: 38415925 Free PMC article.
Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer.
Hughson AL, Hannon G, Salama NA, Vrooman TG, Stockwell CA, Mills BN, Garrett-Larsen J, Qiu H, Katerji R, Benoodt L, Johnston CJ, Murphy JD, Kruger E, Ye J, Gavras NW, Keeley DC, Qin SS, Lesch ML, Muhitch JB, Love TMT, Calvi LM, Lord EM, Luheshi N, Elyes J, Linehan DC, Gerber SA. Hughson AL, et al. Among authors: linehan dc. bioRxiv [Preprint]. 2023 Nov 2:2023.10.30.564833. doi: 10.1101/2023.10.30.564833. bioRxiv. 2023. PMID: 37961513 Free PMC article. Preprint.
New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy.
Uccello TP, Lesch ML, Kintzel SA, Gradzewicz LB, Lamrous L, Murphy SP, Fleming FJ, Mills BN, Murphy JD, Hughson A, Hannon G, Garrett-Larsen J, Qiu H, Drage MG, Ye J, Gavras NW, Keeley DC, Love TMT, Repasky EA, Lord EM, Linehan DC, Gerber SA. Uccello TP, et al. Among authors: linehan dc. Cell Death Dis. 2023 Jul 26;14(7):470. doi: 10.1038/s41419-023-05999-3. Cell Death Dis. 2023. PMID: 37495596 Free PMC article.
Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1.
Khazan N, Quarato ER, Singh NA, Snyder CWA, Moore T, Miller JP, Yasui M, Teramoto Y, Goto T, Reshi S, Hong J, Zhang N, Pandey D, Srivastava P, Morell A, Kawano H, Kawano Y, Conley T, Sahasrabudhe DM, Yano N, Miyamoto H, Aljitawi O, Liesveld J, Becker MW, Calvi LM, Zhovmer AS, Tabdanov ED, Dokholyan NV, Linehan DC, Hansen JN, Gerber SA, Sharon A, Khera MK, Jurutka PW, Rochel N, Kim KK, Rowswell-Turner RB, Singh RK, Moore RG. Khazan N, et al. Among authors: linehan dc. Cancers (Basel). 2023 Jun 30;15(13):3432. doi: 10.3390/cancers15133432. Cancers (Basel). 2023. PMID: 37444542 Free PMC article.
143 results