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Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models.
Miller SR, Luxem K, Lauderdale K, Nambiar P, Honma PS, Ly KK, Bangera S, Bullock M, Shin J, Kaliss N, Qiu Y, Cai C, Shen K, Mallen KD, Yan Z, Mendiola AS, Saito T, Saido TC, Pico AR, Thomas R, Roberson ED, Akassoglou K, Bauer P, Remy S, Palop JJ. Miller SR, et al. Among authors: bauer p. Cell Rep. 2024 Nov 26;43(11):114870. doi: 10.1016/j.celrep.2024.114870. Epub 2024 Oct 19. Cell Rep. 2024. PMID: 39427315 Free article.
Hyperactivation of human acidic chitinase (Chia) for potential medical use.
Okawa K, Kijima M, Ishii M, Nanako M, Yasumura Y, Sakaguchi M, Kimura M, Uehara M, Tabata E, Bauer PO, Oyama F. Okawa K, et al. Among authors: bauer po. J Biol Chem. 2024 Dec 18:108100. doi: 10.1016/j.jbc.2024.108100. Online ahead of print. J Biol Chem. 2024. PMID: 39706263 Free article.
African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1.
Álvarez Jerez P, Wild Crea P, Ramos DM, Gustavsson EK, Radefeldt M, Damianov A, Makarious MB, Ojo OO, Billingsley KJ, Malik L, Daida K, Bromberek S, Hu F, Schneider Z, Surapaneni AL, Stadler J, Rizig M, Morris HR, Pantazis CB, Leonard HL, Screven L, Qi YA, Nalls MA, Bandres-Ciga S, Hardy J, Houlden H, Eng C, Burchard EG, Kachuri L, Lin CH, Black DL; Global Parkinson’s Genetics Program (GP2); Singleton AB, Fischer S, Bauer P, Reed X, Ryten M, Beetz C, Ward M, Okubadejo NU, Blauwendraat C. Álvarez Jerez P, et al. Among authors: bauer p. Nat Struct Mol Biol. 2024 Dec;31(12):1955-1963. doi: 10.1038/s41594-024-01423-2. Epub 2024 Dec 12. Nat Struct Mol Biol. 2024. PMID: 39668204 Free PMC article.
Exploring environmental modifiers of LRRK2-associated Parkinson's disease penetrance: An exposomics and metagenomics pilot study on household dust.
Talavera Andújar B, Pereira SL, Busi SB, Usnich T, Borsche M, Ertan S, Bauer P, Rolfs A, Hezzaz S, Ghelfi J, Brüggemann N, Antony P, Wilmes P, Klein C, Grünewald A, Schymanski EL. Talavera Andújar B, et al. Among authors: bauer p. Environ Int. 2024 Dec;194:109151. doi: 10.1016/j.envint.2024.109151. Epub 2024 Nov 16. Environ Int. 2024. PMID: 39571299 Free article.
1,687 results