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Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models.
Miller SR, Luxem K, Lauderdale K, Nambiar P, Honma PS, Ly KK, Bangera S, Bullock M, Shin J, Kaliss N, Qiu Y, Cai C, Shen K, Mallen KD, Yan Z, Mendiola AS, Saito T, Saido TC, Pico AR, Thomas R, Roberson ED, Akassoglou K, Bauer P, Remy S, Palop JJ. Miller SR, et al. Among authors: yan z. Cell Rep. 2024 Nov 26;43(11):114870. doi: 10.1016/j.celrep.2024.114870. Epub 2024 Oct 19. Cell Rep. 2024. PMID: 39427315 Free article.
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling.
Mendiola AS, Yan Z, Dixit K, Johnson JR, Bouhaddou M, Meyer-Franke A, Shin MG, Yong Y, Agrawal A, MacDonald E, Muthukumar G, Pearce C, Arun N, Cabriga B, Meza-Acevedo R, Alzamora MDPS, Zamvil SS, Pico AR, Ryu JK, Krogan NJ, Akassoglou K. Mendiola AS, et al. Among authors: yan z. Nat Immunol. 2023 Jul;24(7):1173-1187. doi: 10.1038/s41590-023-01522-0. Epub 2023 Jun 8. Nat Immunol. 2023. PMID: 37291385 Free PMC article.
Microglial Gi-dependent dynamics regulate brain network hyperexcitability.
Merlini M, Rafalski VA, Ma K, Kim KY, Bushong EA, Rios Coronado PE, Yan Z, Mendiola AS, Sozmen EG, Ryu JK, Haberl MG, Madany M, Sampson DN, Petersen MA, Bardehle S, Tognatta R, Dean T Jr, Acevedo RM, Cabriga B, Thomas R, Coughlin SR, Ellisman MH, Palop JJ, Akassoglou K. Merlini M, et al. Among authors: yan z. Nat Neurosci. 2021 Jan;24(1):19-23. doi: 10.1038/s41593-020-00756-7. Epub 2020 Dec 14. Nat Neurosci. 2021. PMID: 33318667 Free PMC article.
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.
Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Rios Coronado PE, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K. Mendiola AS, et al. Among authors: yan z. Nat Immunol. 2020 May;21(5):513-524. doi: 10.1038/s41590-020-0654-0. Epub 2020 Apr 13. Nat Immunol. 2020. PMID: 32284594 Free PMC article.
Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.
Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Coronado PER, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K. Mendiola AS, et al. Among authors: yan z. Nat Immunol. 2020 Sep;21(9):1135. doi: 10.1038/s41590-020-0754-x. Nat Immunol. 2020. PMID: 32661365
Fibrin drives thromboinflammation and neuropathology in COVID-19.
Ryu JK, Yan Z, Montano M, Sozmen EG, Dixit K, Suryawanshi RK, Matsui Y, Helmy E, Kaushal P, Makanani SK, Deerinck TJ, Meyer-Franke A, Rios Coronado PE, Trevino TN, Shin MG, Tognatta R, Liu Y, Schuck R, Le L, Miyajima H, Mendiola AS, Arun N, Guo B, Taha TY, Agrawal A, MacDonald E, Aries O, Yan A, Weaver O, Petersen MA, Meza Acevedo R, Alzamora MDPS, Thomas R, Traglia M, Kouznetsova VL, Tsigelny IF, Pico AR, Red-Horse K, Ellisman MH, Krogan NJ, Bouhaddou M, Ott M, Greene WC, Akassoglou K. Ryu JK, et al. Among authors: yan a, yan z. Nature. 2024 Sep;633(8031):905-913. doi: 10.1038/s41586-024-07873-4. Epub 2024 Aug 28. Nature. 2024. PMID: 39198643 Free PMC article.
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