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Senescence-related genes are associated with the immunopathology signature of American Tegumentary Leishmaniasis lesions and may predict progression to mucosal leishmaniasis.
Fantecelle CH, Polaco Covre L, Lopes PO, Sarmento IV, Decote-Ricardo D, Geraldo Freire de Lima C, de Matos Guedes HL, Pimentel MIF, Conceição-Silva F, Maretti-Mira AC, Borges VM, Pedreira de Carvalho L, de Carvalho EM, Mosser D, Falqueto A, Akbar AN, Gomes DCO. Fantecelle CH, et al. Among authors: mosser d. Clin Exp Immunol. 2024 Oct 21:uxae088. doi: 10.1093/cei/uxae088. Online ahead of print. Clin Exp Immunol. 2024. PMID: 39428748
NKG2C+CD57+ natural killer cells with senescent features are induced during cutaneous leishmaniasis and accumulate in patients with lesional healing impairment.
Covre LP, Fantecelle CH, Queiroz AM, Fardin JM, Miranda PH, Henson S, Fonseca-Martins AMD, de Matos Guedes HL, Mosser D, Falqueto A, Akbar A, Gomes DCO. Covre LP, et al. Among authors: mosser d. Clin Exp Immunol. 2024 Aug 9;217(3):279-290. doi: 10.1093/cei/uxae040. Clin Exp Immunol. 2024. PMID: 38700066
Lesional senescent CD4+ T cells mediate bystander cytolysis and contribute to the skin pathology of human cutaneous leishmaniasis.
Covre LP, Fantecelle CH, Garcia de Moura R, Oliveira Lopes P, Sarmento IV, Freire-de-Lima CG, Decote-Ricardo D, de Matos Guedes HL, da Fonsceca-Martins AM, de Carvalho LP, de Carvalho EM, Mosser DM, Falqueto A, Akbar AN, Gomes DCO. Covre LP, et al. Among authors: mosser dm. Front Immunol. 2024 Oct 21;15:1475146. doi: 10.3389/fimmu.2024.1475146. eCollection 2024. Front Immunol. 2024. PMID: 39497830 Free PMC article.
PD-1 Blockade Modulates Functional Activities of Exhausted-Like T Cell in Patients With Cutaneous Leishmaniasis.
Garcia de Moura R, Covre LP, Fantecelle CH, Gajardo VAT, Cunha CB, Stringari LL, Belew AT, Daniel CB, Zeidler SVV, Tadokoro CE, de Matos Guedes HL, Zanotti RL, Mosser D, Falqueto A, Akbar AN, Gomes DCO. Garcia de Moura R, et al. Among authors: mosser d. Front Immunol. 2021 Mar 9;12:632667. doi: 10.3389/fimmu.2021.632667. eCollection 2021. Front Immunol. 2021. PMID: 33767700 Free PMC article.
223 results