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Estrogen receptor alpha deficiency in cardiomyocytes reprograms the heart-derived extracellular vesicle proteome and induces obesity in female mice.
Tham YK, Bernardo BC, Claridge B, Yildiz GS, Woon LM, Bond S, Fang H, Ooi JYY, Matsumoto A, Luo J, Tai CMK, Harmawan CA, Kiriazis H, Donner DG, Mellett NA, Abel ED, Khan SA, De Souza DP, Doomun SNE, Liu K, Xiang R, Singh M, Inouye M, Meikle PJ, Weeks KL, Drew BG, Greening DW, McMullen JR. Tham YK, et al. Nat Cardiovasc Res. 2023 Mar;2(3):268-289. doi: 10.1038/s44161-023-00223-z. Epub 2023 Mar 9. Nat Cardiovasc Res. 2023. PMID: 39196021
FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K.
Weeks KL, Tham YK, Yildiz SG, Alexander Y, Donner DG, Kiriazis H, Harmawan CA, Hsu A, Bernardo BC, Matsumoto A, DePinho RA, Abel ED, Woodcock EA, McMullen JR. Weeks KL, et al. Among authors: tham yk. Am J Physiol Heart Circ Physiol. 2021 Apr 1;320(4):H1470-H1485. doi: 10.1152/ajpheart.00838.2020. Epub 2021 Feb 12. Am J Physiol Heart Circ Physiol. 2021. PMID: 33577435 Free article.
Gene delivery of medium chain acyl-coenzyme A dehydrogenase induces physiological cardiac hypertrophy and protects against pathological remodelling.
Bernardo BC, Weeks KL, Pongsukwechkul T, Gao X, Kiriazis H, Cemerlang N, Boey EJH, Tham YK, Johnson CJ, Qian H, Du XJ, Gregorevic P, McMullen JR. Bernardo BC, et al. Among authors: tham yk. Clin Sci (Lond). 2018 Feb 8;132(3):381-397. doi: 10.1042/CS20171269. Print 2018 Feb 14. Clin Sci (Lond). 2018. PMID: 29358507
Distinct lipidomic profiles in models of physiological and pathological cardiac remodeling, and potential therapeutic strategies.
Tham YK, Huynh K, Mellett NA, Henstridge DC, Kiriazis H, Ooi JYY, Matsumoto A, Patterson NL, Sadoshima J, Meikle PJ, McMullen JR. Tham YK, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Mar;1863(3):219-234. doi: 10.1016/j.bbalip.2017.12.003. Epub 2017 Dec 6. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29217479
Phosphoinositide 3-kinase p110α is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction.
Weeks KL, Gao X, Du XJ, Boey EJ, Matsumoto A, Bernardo BC, Kiriazis H, Cemerlang N, Tan JW, Tham YK, Franke TF, Qian H, Bogoyevitch MA, Woodcock EA, Febbraio MA, Gregorevic P, McMullen JR. Weeks KL, et al. Among authors: tham yk. Circ Heart Fail. 2012 Jul 1;5(4):523-34. doi: 10.1161/CIRCHEARTFAILURE.112.966622. Epub 2012 Jun 15. Circ Heart Fail. 2012. PMID: 22705768
16 results