Vinogradov AA - Search Results

1

Selective pH-Responsive Conjugation between a Pair of De Novo Discovered Peptides.

Ohno Y, Vinogradov AA, Suga H. Ohno Y, et al. Among authors: vinogradov aa. J Am Chem Soc. 2024 Oct 30;146(43):29429-29440. doi: 10.1021/jacs.4c08520. Epub 2024 Oct 21. J Am Chem Soc. 2024. PMID: 39432830

2

Flexizyme-Enabled Benchtop Biosynthesis of Thiopeptides.

Fleming SR, Bartges TE, Vinogradov AA, Kirkpatrick CL, Goto Y, Suga H, Hicks LM, Bowers AA. Fleming SR, et al. Among authors: vinogradov aa. J Am Chem Soc. 2019 Jan 16;141(2):758-762. doi: 10.1021/jacs.8b11521. Epub 2019 Jan 8. J Am Chem Soc. 2019. PMID: 30602112 Free PMC article.

3

Macrocyclic Peptides as Drug Candidates: Recent Progress and Remaining Challenges.

Vinogradov AA, Yin Y, Suga H. Vinogradov AA, et al. J Am Chem Soc. 2019 Mar 13;141(10):4167-4181. doi: 10.1021/jacs.8b13178. Epub 2019 Feb 27. J Am Chem Soc. 2019. PMID: 30768253 Review.

4

Minimal lactazole scaffold for in vitro thiopeptide bioengineering.

Vinogradov AA, Shimomura M, Goto Y, Ozaki T, Asamizu S, Sugai Y, Suga H, Onaka H. Vinogradov AA, et al. Nat Commun. 2020 May 8;11(1):2272. doi: 10.1038/s41467-020-16145-4. Nat Commun. 2020. PMID: 32385237 Free PMC article.

5

Promiscuous Enzymes Cooperate at the Substrate Level En Route to Lactazole A.

Vinogradov AA, Shimomura M, Kano N, Goto Y, Onaka H, Suga H. Vinogradov AA, et al. J Am Chem Soc. 2020 Aug 12;142(32):13886-13897. doi: 10.1021/jacs.0c05541. Epub 2020 Jul 31. J Am Chem Soc. 2020. PMID: 32664727

6

Introduction to Thiopeptides: Biological Activity, Biosynthesis, and Strategies for Functional Reprogramming.

Vinogradov AA, Suga H. Vinogradov AA, et al. Cell Chem Biol. 2020 Aug 20;27(8):1032-1051. doi: 10.1016/j.chembiol.2020.07.003. Epub 2020 Jul 21. Cell Chem Biol. 2020. PMID: 32698017 Free article. Review.

7

Accurate Broadcasting of Substrate Fitness for Lactazole Biosynthetic Pathway from Reactivity-Profiling mRNA Display.

Vinogradov AA, Nagai E, Chang JS, Narumi K, Onaka H, Goto Y, Suga H. Vinogradov AA, et al. J Am Chem Soc. 2020 Nov 19. doi: 10.1021/jacs.0c10374. Online ahead of print. J Am Chem Soc. 2020. PMID: 33211968

8

Site-Specific Nonenzymatic Peptide S/O-Glutamylation Reveals the Extent of Substrate Promiscuity in Glutamate Elimination Domains.

Vinogradov AA, Nagano M, Goto Y, Suga H. Vinogradov AA, et al. J Am Chem Soc. 2021 Aug 25;143(33):13358-13369. doi: 10.1021/jacs.1c06470. Epub 2021 Aug 15. J Am Chem Soc. 2021. PMID: 34392675 Free article.

9

Accurate Models of Substrate Preferences of Post-Translational Modification Enzymes from a Combination of mRNA Display and Deep Learning.

Vinogradov AA, Chang JS, Onaka H, Goto Y, Suga H. Vinogradov AA, et al. ACS Cent Sci. 2022 Jun 22;8(6):814-824. doi: 10.1021/acscentsci.2c00223. Epub 2022 May 26. ACS Cent Sci. 2022. PMID: 35756369 Free PMC article.

10

De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors.

Vinogradov AA, Zhang Y, Hamada K, Chang JS, Okada C, Nishimura H, Terasaka N, Goto Y, Ogata K, Sengoku T, Onaka H, Suga H. Vinogradov AA, et al. J Am Chem Soc. 2022 Nov 9;144(44):20332-20341. doi: 10.1021/jacs.2c07937. Epub 2022 Oct 25. J Am Chem Soc. 2022. PMID: 36282922 Free PMC article.

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