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Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis.
Ackermann T, Shokry E, Deshmukh R, Anand J, Galbraith LCA, Mitchell L, Rodriguez-Blanco G, Villar VH, Sterken BA, Nixon C, Zanivan S, Blyth K, Sumpton D, Tardito S. Ackermann T, et al. Among authors: galbraith lca. EMBO Mol Med. 2024 Nov;16(11):2749-2774. doi: 10.1038/s44321-024-00142-x. Epub 2024 Oct 21. EMBO Mol Med. 2024. PMID: 39433871 Free PMC article.
SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer.
Martinez RS, Salji MJ, Rushworth L, Ntala C, Rodriguez Blanco G, Hedley A, Clark W, Peixoto P, Hervouet E, Renaude E, Kung SHY, Galbraith LCA, Nixon C, Lilla S, MacKay GM, Fazli L, Gaughan L, Sumpton D, Gleave ME, Zanivan S, Blomme A, Leung HY. Martinez RS, et al. Among authors: galbraith lca. Cancer Res. 2021 Jul 1;81(13):3664-3678. doi: 10.1158/0008-5472.CAN-20-3694. Epub 2021 May 13. Cancer Res. 2021. PMID: 33985973 Free article.
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function.
Román-Fernández A, Mansour MA, Kugeratski FG, Anand J, Sandilands E, Galbraith L, Rakovic K, Freckmann EC, Cumming EM, Park J, Nikolatou K, Lilla S, Shaw R, Strachan D, Mason S, Patel R, McGarry L, Katoch A, Campbell KJ, Nixon C, Miller CJ, Leung HY, Le Quesne J, Norman JC, Zanivan S, Blyth K, Bryant DM. Román-Fernández A, et al. Sci Adv. 2023 Feb 3;9(5):eabq1858. doi: 10.1126/sciadv.abq1858. Epub 2023 Feb 3. Sci Adv. 2023. PMID: 36735782 Free PMC article.
An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism.
Nacke M, Sandilands E, Nikolatou K, Román-Fernández Á, Mason S, Patel R, Lilla S, Yelland T, Galbraith LCA, Freckmann EC, McGarry L, Morton JP, Shanks E, Leung HY, Markert E, Ismail S, Zanivan S, Blyth K, Bryant DM. Nacke M, et al. Among authors: galbraith lca. Nat Commun. 2021 Mar 12;12(1):1623. doi: 10.1038/s41467-021-21847-4. Nat Commun. 2021. PMID: 33712589 Free PMC article.
Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells.
Baenke F, Chaneton B, Smith M, Van Den Broek N, Hogan K, Tang H, Viros A, Martin M, Galbraith L, Girotti MR, Dhomen N, Gottlieb E, Marais R. Baenke F, et al. Mol Oncol. 2016 Jan;10(1):73-84. doi: 10.1016/j.molonc.2015.08.003. Epub 2015 Aug 20. Mol Oncol. 2016. PMID: 26365896 Free PMC article.
Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer.
Ahmad I, Mui E, Galbraith L, Patel R, Tan EH, Salji M, Rust AG, Repiscak P, Hedley A, Markert E, Loveridge C, van der Weyden L, Edwards J, Sansom OJ, Adams DJ, Leung HY. Ahmad I, et al. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8290-5. doi: 10.1073/pnas.1601571113. Epub 2016 Jun 29. Proc Natl Acad Sci U S A. 2016. PMID: 27357679 Free PMC article.
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