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Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis.
Ackermann T, Shokry E, Deshmukh R, Anand J, Galbraith LCA, Mitchell L, Rodriguez-Blanco G, Villar VH, Sterken BA, Nixon C, Zanivan S, Blyth K, Sumpton D, Tardito S. Ackermann T, et al. Among authors: mitchell l. EMBO Mol Med. 2024 Nov;16(11):2749-2774. doi: 10.1038/s44321-024-00142-x. Epub 2024 Oct 21. EMBO Mol Med. 2024. PMID: 39433871 Free PMC article.
The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis.
Clarke CJ, Berg TJ, Birch J, Ennis D, Mitchell L, Cloix C, Campbell A, Sumpton D, Nixon C, Campbell K, Bridgeman VL, Vermeulen PB, Foo S, Kostaras E, Jones JL, Haywood L, Pulleine E, Yin H, Strathdee D, Sansom O, Blyth K, McNeish I, Zanivan S, Reynolds AR, Norman JC. Clarke CJ, et al. Among authors: mitchell l. Curr Biol. 2016 Mar 21;26(6):755-65. doi: 10.1016/j.cub.2016.01.045. Epub 2016 Mar 3. Curr Biol. 2016. PMID: 26948875 Free PMC article.
Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels.
Novo D, Heath N, Mitchell L, Caligiuri G, MacFarlane A, Reijmer D, Charlton L, Knight J, Calka M, McGhee E, Dornier E, Sumpton D, Mason S, Echard A, Klinkert K, Secklehner J, Kruiswijk F, Vousden K, Macpherson IR, Blyth K, Bailey P, Yin H, Carlin LM, Morton J, Zanivan S, Norman JC. Novo D, et al. Among authors: mitchell l. Nat Commun. 2018 Nov 29;9(1):5069. doi: 10.1038/s41467-018-07339-y. Nat Commun. 2018. PMID: 30498210 Free PMC article.
Correction: BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration.
Loveridge CJ, Slater S, Campbell KJ, Nam NA, Knight J, Ahmad I, Hedley A, Lilla S, Repiscak P, Patel R, Salji M, Fleming J, Mitchell L, Nixon C, Strathdee D, Neilson M, Ntala C, Bryson S, Zanivan S, Edwards J, Robson CN, Goodyear CS, Blyth K, Leung HY. Loveridge CJ, et al. Among authors: mitchell l. Oncogene. 2020 Mar;39(11):2450. doi: 10.1038/s41388-019-1149-z. Oncogene. 2020. PMID: 31857667 Free PMC article.
BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration.
Loveridge CJ, Slater S, Campbell KJ, Nam NA, Knight J, Ahmad I, Hedley A, Lilla S, Repiscak P, Patel R, Salji M, Fleming J, Mitchell L, Nixon C, Strathdee D, Neilson M, Ntala C, Bryson S, Zanivan S, Edwards J, Robson CN, Goodyear CS, Blyth K, Leung HY. Loveridge CJ, et al. Among authors: mitchell l. Oncogene. 2020 Feb;39(8):1797-1806. doi: 10.1038/s41388-019-1106-x. Epub 2019 Nov 18. Oncogene. 2020. PMID: 31740786 Free PMC article.
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma.
Mahmood M, Liu EM, Shergold AL, Tolla E, Tait-Mulder J, Huerta-Uribe A, Shokry E, Young AL, Lilla S, Kim M, Park T, Boscenco S, Manchon JL, Rodríguez-Antona C, Walters RC, Springett RJ, Blaza JN, Mitchell L, Blyth K, Zanivan S, Sumpton D, Roberts EW, Reznik E, Gammage PA. Mahmood M, et al. Among authors: mitchell l. Nat Cancer. 2024 Apr;5(4):659-672. doi: 10.1038/s43018-023-00721-w. Epub 2024 Jan 29. Nat Cancer. 2024. PMID: 38286828 Free PMC article.
1,824 results