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Page 1
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Arias-Vasquez A, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MPM, Boomsma DI, Brodaty H, Brouwer RM, Buitelaar JK, Burkhardt R, Cahn W, Calhoun VD, Carmichael OT, Chakravarty M, Chen Q, Ching CRK, Cichon S, Crespo-Facorro B, Crivello F, Dale AM, Smith GD, de Geus EJC, De Jager PL, de Zubicaray GI, Debette S, DeCarli C, Depondt C, Desrivières S, Djurovic S, Ehrlich S, Erk S, Espeseth T, Fernández G, Filippi I, Fisher SE, Fleischman DA, Fletcher E, Fornage M, Forstner AJ, Francks C, Franke B, Ge T, Goldman AL, Grabe HJ, Green RC, Grimm O, Groenewold NA, Gruber O, Gudnason V, Håberg AK, Haukvik UK, Heinz A, Hibar DP, Hilal S, Himali JJ, Ho BC, Hoehn DF, Hoekstra PJ, Hofer E, Hoffmann W, Holmes AJ, Homuth G, Hosten N, Ikram MK, Ipser JC, Jack CR Jr, Jahanshad N, Jönsson EG, Kahn RS, Kanai R, Klein M, Knol MJ, Launer LJ, Lawrie SM, Hellard SL, Lee PH, Lemaître H, Li S, Liewald DCM, Lin H, Longstreth WT Jr, Lopez OL, Luciano M, Maillard P, Marquand AF, Martin NG, Martin… See abstract for full author list ➔ García-Marín LM, et al. Among authors: de jager pl, de zubicaray gi, de geus ejc. Nat Genet. 2024 Nov;56(11):2333-2344. doi: 10.1038/s41588-024-01951-z. Epub 2024 Oct 21. Nat Genet. 2024. PMID: 39433889
Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes.
Rietschel L, Streit F, Zhu G, McAloney K, Frank J, Couvy-Duchesne B, Witt SH, Binz TM; CORtisolNETwork (CORNET) Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC); McGrath J, Hickie IB, Hansell NK, Wright MJ, Gillespie NA, Forstner AJ, Schulze TG, Wüst S, Nöthen MM, Baumgartner MR, Walker BR, Crawford AA, Colodro-Conde L, Medland SE, Martin NG, Rietschel M. Rietschel L, et al. Sci Rep. 2017 Nov 10;7(1):15351. doi: 10.1038/s41598-017-11852-3. Sci Rep. 2017. PMID: 29127340 Free PMC article. Clinical Trial.
Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.
Oveisgharan S, Yang J, Yu L, Burba D, Bang W, Tasaki S, Grodstein F, Wang Y, Zhao J, De Jager PL, Schneider JA, Bennett DA. Oveisgharan S, et al. Among authors: de jager pl. Neurology. 2023 Apr 4;100(14):e1474-e1487. doi: 10.1212/WNL.0000000000206833. Epub 2023 Jan 25. Neurology. 2023. PMID: 36697247 Free PMC article.
Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts.
Zhou W, Karan KR, Gu W, Klein HU, Sturm G, De Jager PL, Bennett DA, Hirano M, Picard M, Mills RE. Zhou W, et al. Among authors: de jager pl. bioRxiv [Preprint]. 2023 Apr 21:2023.02.03.527065. doi: 10.1101/2023.02.03.527065. bioRxiv. 2023. Update in: PLoS Biol. 2024 Aug 22;22(8):e3002723. doi: 10.1371/journal.pbio.3002723 PMID: 36778249 Free PMC article. Updated. Preprint.
Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings.
Sasse A, Ng B, Spiro AE, Tasaki S, Bennett DA, Gaiteri C, De Jager PL, Chikina M, Mostafavi S. Sasse A, et al. Among authors: de jager pl. bioRxiv [Preprint]. 2023 Sep 28:2023.03.16.532969. doi: 10.1101/2023.03.16.532969. bioRxiv. 2023. Update in: Nat Genet. 2023 Dec;55(12):2060-2064. doi: 10.1038/s41588-023-01524-6 PMID: 36993652 Free PMC article. Updated. Preprint.
Primacy and recency effects in verbal memory are differentially associated with post-mortem frontal cortex p-tau 217 and 202 levels in a mixed sample of community-dwelling older adults.
Gicas KM, Honer WG, Petyuk VA, Wilson RS, Boyle PA, Leurgans SE, Schneider JA, De Jager PL, Bennett DA. Gicas KM, et al. Among authors: de jager pl. J Clin Exp Neuropsychol. 2023 Oct;45(8):770-785. doi: 10.1080/13803395.2023.2232583. Epub 2023 Jul 13. J Clin Exp Neuropsychol. 2023. PMID: 37440260 Free PMC article.
Associations of brain morphology with cortical proteins of cognitive resilience.
Poole VN, Ridwan AR, Arfanakis K, Dawe RJ, Seyfried NT, De Jager PL, Schneider JA, Leurgans SE, Yu L, Bennett DA. Poole VN, et al. Among authors: de jager pl. Neurobiol Aging. 2024 May;137:1-7. doi: 10.1016/j.neurobiolaging.2024.02.005. Epub 2024 Feb 15. Neurobiol Aging. 2024. PMID: 38394722
589 results