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Mutant induced neurons and humanized mice enable identification of Niemann-Pick type C1 proteostatic therapies.
Azaria RD, Correia AB, Schache KJ, Zapata M, Pathmasiri KC, Mohanty V, Nannapaneni DT, Ashfeld BL, Helquist P, Wiest O, Ohgane K, Li Q, Fredenburg RA, Blagg BS, Cologna SM, Schultz ML, Lieberman AP. Azaria RD, et al. Among authors: lieberman ap. JCI Insight. 2024 Aug 29;9(20):e179525. doi: 10.1172/jci.insight.179525. JCI Insight. 2024. PMID: 39207850 Free PMC article.
Accumulation of TMEM106B C-terminal fragments in Niemann-Pick type C disease.
Azaria RD, Ferris SP, Tashjian RS, Perneel J, Van den Broeck M, Mackenzie IR, Berry-Kravis E, Rademakers R, Lieberman AP. Azaria RD, et al. Among authors: lieberman ap. J Neuropathol Exp Neurol. 2024 Nov 1;83(11):984-986. doi: 10.1093/jnen/nlae072. J Neuropathol Exp Neurol. 2024. PMID: 38964371 No abstract available.
The status of digital pathology and associated infrastructure within Alzheimer's Disease Centers.
Scalco R, Hamsafar Y, White CL, Schneider JA, Reichard RR, Prokop S, Perrin RJ, Nelson PT, Mooney S, Lieberman AP, Kukull WA, Kofler J, Keene CD, Kapasi A, Irwin DJ, Gutman DA, Flanagan ME, Crary JF, Chan KC, Murray ME, Dugger BN. Scalco R, et al. Among authors: lieberman ap. J Neuropathol Exp Neurol. 2023 Feb 21;82(3):202-211. doi: 10.1093/jnen/nlac127. J Neuropathol Exp Neurol. 2023. PMID: 36692179 Free PMC article.
Niemann-Pick C1 protein regulates platelet membrane-associated calcium ion signaling in thrombo-occlusive diseases in mice.
Manke MC, Roslan A, Walker B, Münzer P, Kollotzek F, Peng B, Mencl S, Coman C, Szepanowski RD, Schulze H, Lieberman AP, Lang F, Gawaz M, Kleinschnitz C, Lukowski R, Ahrends R, Bobe R, Borst O. Manke MC, et al. Among authors: lieberman ap. J Thromb Haemost. 2023 Jul;21(7):1957-1966. doi: 10.1016/j.jtha.2023.03.038. Epub 2023 Apr 11. J Thromb Haemost. 2023. PMID: 37054918 Free article.
Amyloid-β predominant Alzheimer's disease neuropathologic change.
Kovacs GG, Katsumata Y, Wu X, Aung KZ, Fardo DW, Forrest SL; Alzheimer's Disease Genetics Consortium; Nelson PT. Kovacs GG, et al. Brain. 2024 Oct 17:awae325. doi: 10.1093/brain/awae325. Online ahead of print. Brain. 2024. PMID: 39417691
Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice.
Yuan T, Kumar S, Skinner ME, Victor-Joseph R, Abuaita M, Keijer J, Zhang J, Kunkel TJ, Liu Y, Petrunak EM, Saunders TL, Lieberman AP, Stuckey JA, Neamati N, Al-Murshedi F, Alfadhel M, Spelbrink JN, Rodenburg R, de Boer VCJ, Lombard DB. Yuan T, et al. Among authors: lieberman ap. iScience. 2024 May 15;27(6):109991. doi: 10.1016/j.isci.2024.109991. eCollection 2024 Jun 21. iScience. 2024. PMID: 38846003 Free PMC article.
182 results