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Genetic iron overload aggravates, and pharmacological iron restriction improves, MDS pathophysiology in a preclinical study.
Blood. 2025 Jan 9;145(2):155-169. doi: 10.1182/blood.2024026135.
Blood. 2025.
PMID: 39437711
Macrophage metabolic rewiring improves heme-suppressed efferocytosis and tissue damage in sickle cell disease.
Sharma R, Antypiuk A, Vance SZ, Manwani D, Pearce Q, Cox JE, An X, Yazdanbakhsh K, Vinchi F.
Sharma R, et al. Among authors: antypiuk a.
Blood. 2023 Jun 22;141(25):3091-3108. doi: 10.1182/blood.2022018026.
Blood. 2023.
PMID: 36952641
Free PMC article.
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Iron therapy mitigates chronic kidney disease progression by regulating intracellular iron status of kidney macrophages.
Patino E, Bhatia D, Vance SZ, Antypiuk A, Uni R, Campbell C, Castillo CG, Jaouni S, Vinchi F, Choi ME, Akchurin O.
Patino E, et al. Among authors: antypiuk a.
JCI Insight. 2023 Jan 10;8(1):e159235. doi: 10.1172/jci.insight.159235.
JCI Insight. 2023.
PMID: 36394951
Free PMC article.
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