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Docosahexaenoic acid enhances the treatment efficacy for castration-resistant prostate cancer by inhibiting autophagy through Atg4B inhibition.
Kudo Y, Nakamura K, Tsuzuki H, Hirota K, Kawai M, Takaya D, Fukuzawa K, Honma T, Yoshino Y, Nakamura M, Shiota M, Fujimoto N, Ikari A, Endo S. Kudo Y, et al. Among authors: takaya d. Arch Biochem Biophys. 2024 Oct;760:110135. doi: 10.1016/j.abb.2024.110135. Epub 2024 Aug 23. Arch Biochem Biophys. 2024. PMID: 39181384 Free article.
New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2-((coumarin-5-yl)oxy)alkanoyl moiety.
Cho N, Kikuzato K, Futamura Y, Shimizu T, Hayase H, Kamisaka K, Takaya D, Yuki H, Honma T, Niikura M, Kobayashi F, Watanabe N, Osada H, Koyama H. Cho N, et al. Among authors: takaya d. Bioorg Med Chem. 2022 Jul 15;66:116830. doi: 10.1016/j.bmc.2022.116830. Epub 2022 May 14. Bioorg Med Chem. 2022. PMID: 35594648
Pharmacological intervention of cholesterol sulfate-mediated T cell exclusion promotes antitumor immunity.
Tatsuguchi T, Uruno T, Sugiura Y, Oisaki K, Takaya D, Sakata D, Izumi Y, Togo T, Hattori Y, Kunimura K, Sakurai T, Honma T, Bamba T, Nakamura M, Kanai M, Suematsu M, Fukui Y. Tatsuguchi T, et al. Among authors: takaya d. Biochem Biophys Res Commun. 2022 Jun 18;609:183-188. doi: 10.1016/j.bbrc.2022.04.035. Epub 2022 Apr 10. Biochem Biophys Res Commun. 2022. PMID: 35452959 Free article.
Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Inaba K, Ebihara K, Senda M, Yoshino R, Sakuma C, Koiwai K, Takaya D, Watanabe C, Watanabe A, Kawashima Y, Fukuzawa K, Imamura R, Kojima H, Okabe T, Uemura N, Kasai S, Kanuka H, Nishimura T, Watanabe K, Inoue H, Fujikawa Y, Honma T, Hirokawa T, Senda T, Niwa R. Inaba K, et al. Among authors: takaya d. BMC Biol. 2022 Feb 17;20(1):43. doi: 10.1186/s12915-022-01233-2. BMC Biol. 2022. PMID: 35172816 Free PMC article.
FMODB: The World's First Database of Quantum Mechanical Calculations for Biomacromolecules Based on the Fragment Molecular Orbital Method.
Takaya D, Watanabe C, Nagase S, Kamisaka K, Okiyama Y, Moriwaki H, Yuki H, Sato T, Kurita N, Yagi Y, Takagi T, Kawashita N, Takaba K, Ozawa T, Takimoto-Kamimura M, Tanaka S, Fukuzawa K, Honma T. Takaya D, et al. J Chem Inf Model. 2021 Feb 22;61(2):777-794. doi: 10.1021/acs.jcim.0c01062. Epub 2021 Jan 29. J Chem Inf Model. 2021. PMID: 33511845
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