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PCNA-binding activity separates RNF168 functions in DNA replication and DNA double-stranded break signaling.
Yang Y, Jayaprakash D, Jhujh SS, Reynolds JJ, Chen S, Gao Y, Anand JR, Mutter-Rottmayer E, Ariel P, An J, Cheng X, Pearce KH, Blanchet SA, Nandakumar N, Zhou P, Fradet-Turcotte A, Stewart GS, Vaziri C. Yang Y, et al. Among authors: blanchet sa. Nucleic Acids Res. 2024 Nov 27;52(21):13019-13035. doi: 10.1093/nar/gkae918. Nucleic Acids Res. 2024. PMID: 39445802 Free PMC article.
Human papillomavirus E7 oncoprotein targets RNF168 to hijack the host DNA damage response.
Sitz J, Blanchet SA, Gameiro SF, Biquand E, Morgan TM, Galloy M, Dessapt J, Lavoie EG, Blondeau A, Smith BC, Mymryk JS, Moody CA, Fradet-Turcotte A. Sitz J, et al. Among authors: blanchet sa. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19552-19562. doi: 10.1073/pnas.1906102116. Epub 2019 Sep 9. Proc Natl Acad Sci U S A. 2019. PMID: 31501315 Free PMC article.