Cornelis FMF - Search Results

1

IGF1 drives Wnt-induced joint damage and is a potential therapeutic target for osteoarthritis.

Escribano-Núñez A, Cornelis FMF, De Roover A, Sermon A, Cailotto F, Lories RJ, Monteagudo S. Escribano-Núñez A, et al. Among authors: cornelis fmf. Nat Commun. 2024 Oct 24;15(1):9170. doi: 10.1038/s41467-024-53604-8. Nat Commun. 2024. PMID: 39448593 Free PMC article.

2

DOT1L safeguards cartilage homeostasis and protects against osteoarthritis.

Monteagudo S, Cornelis FMF, Aznar-Lopez C, Yibmantasiri P, Guns LA, Carmeliet P, Cailotto F, Lories RJ. Monteagudo S, et al. Among authors: cornelis fmf. Nat Commun. 2017 Jun 19;8:15889. doi: 10.1038/ncomms15889. Nat Commun. 2017. PMID: 28627522 Free PMC article.

3

Hypoxia induces DOT1L in articular cartilage to protect against osteoarthritis.

De Roover A, Núñez AE, Cornelis FM, Cherifi C, Casas-Fraile L, Sermon A, Cailotto F, Lories RJ, Monteagudo S. De Roover A, et al. JCI Insight. 2021 Dec 22;6(24):e150451. doi: 10.1172/jci.insight.150451. JCI Insight. 2021. PMID: 34727094 Free PMC article.

4

ANP32A represses Wnt signaling across tissues thereby protecting against osteoarthritis and heart disease.

Monteagudo S, Cornelis FMF, Wang X, de Roover A, Peeters T, Quintiens J, Sermon A, de Almeida RC, Meulenbelt I, Lories RJ. Monteagudo S, et al. Among authors: cornelis fmf. Osteoarthritis Cartilage. 2022 May;30(5):724-734. doi: 10.1016/j.joca.2022.02.615. Epub 2022 Feb 25. Osteoarthritis Cartilage. 2022. PMID: 35227892 Free article.

5

Hypoxia and Wnt signaling inversely regulate expression of chondroprotective molecule ANP32A in articular cartilage.

Quintiens J, De Roover A, Cornelis FMF, Escribano-Núñez A, Sermon A, Pazmino S, Monteagudo S, Lories RJ. Quintiens J, et al. Among authors: cornelis fmf. Osteoarthritis Cartilage. 2023 Apr;31(4):507-518. doi: 10.1016/j.joca.2022.10.019. Epub 2022 Nov 10. Osteoarthritis Cartilage. 2023. PMID: 36370958 Free article.

6

Functional effects of susceptibility genes in osteoarthritis.

Cornelis FM, Luyten FP, Lories RJ. Cornelis FM, et al. Discov Med. 2011 Aug;12(63):129-39. Discov Med. 2011. PMID: 21878190 Free article. Review.

7

ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone.

Cornelis FMF, Monteagudo S, Guns LKA, den Hollander W, Nelissen RGHH, Storms L, Peeters T, Jonkers I, Meulenbelt I, Lories RJ. Cornelis FMF, et al. Sci Transl Med. 2018 Sep 12;10(458):eaar8426. doi: 10.1126/scitranslmed.aar8426. Sci Transl Med. 2018. PMID: 30209244

8

Increased susceptibility to develop spontaneous and post-traumatic osteoarthritis in Dot1l-deficient mice.

Cornelis FMF, de Roover A, Storms L, Hens A, Lories RJ, Monteagudo S. Cornelis FMF, et al. Osteoarthritis Cartilage. 2019 Mar;27(3):513-525. doi: 10.1016/j.joca.2018.11.008. Epub 2018 Dec 1. Osteoarthritis Cartilage. 2019. PMID: 30513362 Free article.

9

Exostosin-1 enhances canonical Wnt signaling activity during chondrogenic differentiation.

Wang X, Cornelis FMF, Lories RJ, Monteagudo S. Wang X, et al. Among authors: cornelis fmf. Osteoarthritis Cartilage. 2019 Nov;27(11):1702-1710. doi: 10.1016/j.joca.2019.07.007. Epub 2019 Jul 19. Osteoarthritis Cartilage. 2019. PMID: 31330188 Free article.

10

Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis.

Assi R, Cherifi C, Cornelis FMF, Zhou Q, Storms L, Pazmino S, Coutinho de Almeida R, Meulenbelt I, Lories RJ, Monteagudo S. Assi R, et al. Among authors: cornelis fmf. Ann Rheum Dis. 2023 Jul;82(7):963-973. doi: 10.1136/ard-2022-223789. Epub 2023 Mar 16. Ann Rheum Dis. 2023. PMID: 36927643

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