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Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma.
Hsieh J, Danis EP, Owens CR, Parrish JK, Nowling NL, Wolin AR, Purdy SC, Rosenbaum SR, Ivancevic AM, Chuong EB, Ford HL, Jedlicka P. Hsieh J, et al. Among authors: owens cr. Oncogene. 2025 Jan;44(1):19-29. doi: 10.1038/s41388-024-03201-2. Epub 2024 Oct 24. Oncogene. 2025. PMID: 39448867 Free PMC article.
Androgen Receptor Regulates CD44 Expression in Bladder Cancer.
Sottnik JL, Vanderlinden L, Joshi M, Chauca-Diaz A, Owens C, Hansel DE, Sempeck C, Ghosh D, Theodorescu D. Sottnik JL, et al. Cancer Res. 2021 Jun 1;81(11):2833-2846. doi: 10.1158/0008-5472.CAN-20-3095. Epub 2021 Mar 9. Cancer Res. 2021. PMID: 33687952 Free PMC article.
GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis.
Agarwal N, Dancik GM, Goodspeed A, Costello JC, Owens C, Duex JE, Theodorescu D. Agarwal N, et al. Cancer Res. 2016 Sep 1;76(17):5175-85. doi: 10.1158/0008-5472.CAN-16-1099. Epub 2016 Jun 16. Cancer Res. 2016. PMID: 27312530 Free PMC article.
Metastatic cells are preferentially vulnerable to lysosomal inhibition.
Morgan MJ, Fitzwalter BE, Owens CR, Powers RK, Sottnik JL, Gamez G, Costello JC, Theodorescu D, Thorburn A. Morgan MJ, et al. Among authors: owens cr. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8479-E8488. doi: 10.1073/pnas.1706526115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127018 Free PMC article.
33 results