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Page 1
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma.
Hsieh J, Danis EP, Owens CR, Parrish JK, Nowling NL, Wolin AR, Purdy SC, Rosenbaum SR, Ivancevic AM, Chuong EB, Ford HL, Jedlicka P. Hsieh J, et al. Among authors: rosenbaum sr. Oncogene. 2025 Jan;44(1):19-29. doi: 10.1038/s41388-024-03201-2. Epub 2024 Oct 24. Oncogene. 2025. PMID: 39448867 Free PMC article.
EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression.
Wolin AR, Vincent MY, Hotz T, Purdy SC, Rosenbaum SR, Hughes CJ, Hsu JY, Oliphant MUJ, Armstrong B, Wessells V, Varella-Garcia M, Galbraith MD, Pierce A, Wang D, Venkataraman S, Danis E, Veo B, Serkova N, Espinosa JM, Gustafson DL, Vibhakar R, Ford HL. Wolin AR, et al. Among authors: rosenbaum sr. Neuro Oncol. 2023 Dec 8;25(12):2287-2301. doi: 10.1093/neuonc/noad128. Neuro Oncol. 2023. PMID: 37486991 Free PMC article.
SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death.
Rosenbaum SR, Caksa S, Stefanski CD, Trachtenberg IV, Wilson HP, Wilski NA, Ott CA, Purwin TJ, Haj JI, Pomante D, Kotas D, Chervoneva I, Capparelli C, Aplin AE. Rosenbaum SR, et al. Mol Cancer Res. 2024 Feb 1;22(2):209-220. doi: 10.1158/1541-7786.MCR-23-0290. Mol Cancer Res. 2024. PMID: 37847239 Free PMC article.
FOXD3 Regulates VISTA Expression in Melanoma.
Rosenbaum SR, Knecht M, Mollaee M, Zhong Z, Erkes DA, McCue PA, Chervoneva I, Berger AC, Lo JA, Fisher DE, Gershenwald JE, Davies MA, Purwin TJ, Aplin AE. Rosenbaum SR, et al. Cell Rep. 2020 Jan 14;30(2):510-524.e6. doi: 10.1016/j.celrep.2019.12.036. Cell Rep. 2020. PMID: 31940493 Free PMC article.
CADM1 is a TWIST1-regulated suppressor of invasion and survival.
Hartsough EJ, Weiss MB, Heilman SA, Purwin TJ, Kugel CH 3rd, Rosenbaum SR, Erkes DA, Tiago M, HooKim K, Chervoneva I, Aplin AE. Hartsough EJ, et al. Among authors: rosenbaum sr. Cell Death Dis. 2019 Mar 25;10(4):281. doi: 10.1038/s41419-019-1515-3. Cell Death Dis. 2019. PMID: 30911007 Free PMC article.